Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT04343651 · ClinicalTrials.gov registry record · Phase 2

Study to Evaluate the Efficacy and Safety of Leronlimab for Mild to Moderate COVID-19

A Phase 2 study of Coronavirus Disease 2019, sponsored by CytoDyn.

Completed
Registry status
Phase 2
Development phase
86
Enrollment target
12
Study locations

NCT04343651 is a Phase 2 study of Coronavirus Disease 2019 that has completed, run by CytoDyn. The registered enrollment target is 86 participants, below the 451-participant average among 4 other Coronavirus Disease 2019 trials with a reported enrollment target (81% lower). The trial reports 12 study locations across 9 states.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT04343651, a Phase 2 study of Coronavirus Disease 2019, has completed, sponsored by CytoDyn.

COMPLETED
Registry status
Phase 2
Development phase
86 participants
Enrollment target
12
Study locations

Study Summary

This is a Phase 2, two-arm, randomized, double blind, placebo controlled multicenter study to evaluate the safety and efficacy of leronlimab (PRO 140) in patients with mild-to-moderate symptoms of respiratory illness caused by coronavirus 2019 infection.

Conditions Studied

Interventions

  • DRUG Placebo
  • DRUG Leronlimab (700mg)

Study Locations (12)

California

  • University of California, Los Angeles - Los Angeles
  • Palmtree Clinical Research, Inc. - Palm Springs
  • Eisenhower Health - Rancho Mirage

New York

  • Montefiore Medical Center - The Bronx
  • White Plains Hospital - White Plains

Connecticut

  • Yale - New Haven

Georgia

  • Center for Advanced Research & Education (CARE) - Gainesville

Massachusetts

  • Beth Israel Deaconess Medical Center - Boston

New Jersey

  • Atlantic Health System Hospital - Morristown

North Carolina

  • Novant Health - Charlotte

Ohio

  • Ohio Health - Columbus

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2020-04-01
Est. Completion 2021-09-20
Phase Phase 2

Sponsor

CytoDyn

18 total trials

What the Registry Record Tells You About NCT04343651

The ClinicalTrials.gov registry entry for NCT04343651 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 86 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 451-participant average among 4 other Coronavirus Disease 2019 trials with a reported enrollment target (81% lower). The listed sponsor is CytoDyn, which has 18 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Coronavirus Disease 2019 appearing as the primary indexed condition, and to 2 interventions - of which Placebo is the first listed.

NCT04343651 reports 12 study locations spanning 9 distinct geographic areas - top geographies include California, New York, Connecticut.

Frequently Asked Questions

What is clinical trial NCT04343651 about?

NCT04343651 is a clinical study titled "Study to Evaluate the Efficacy and Safety of Leronlimab for Mild to Moderate COVID-19". This is a Phase 2, two-arm, randomized, double blind, placebo controlled multicenter study to evaluate the safety and efficacy of leronlimab (PRO 140) in patients with mild-to-moderate symptoms of respiratory illness caused by coronavirus 2019 infection.

What is the current status of trial NCT04343651?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 86 participants. The study started on 2020-04-01. Estimated completion is 2021-09-20.

What conditions does trial NCT04343651 study?

This clinical trial studies the following conditions: Coronavirus Disease 2019.

What interventions are being tested in trial NCT04343651?

The interventions under investigation include: Placebo (DRUG), Leronlimab (700mg) (DRUG).

Who is sponsoring clinical trial NCT04343651?

This trial is sponsored by CytoDyn, which has 18 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT04343651 being conducted?

This trial has 12 study locations across California, Connecticut, Georgia, Massachusetts, New Jersey. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Coronavirus Disease 2019

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.