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NCT02038673 · ClinicalTrials.gov registry record · Phase 1

An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors

A Phase 1 study, sponsored by Astellas Pharma.

Completed
Registry status
Phase 1
Development phase
86
Enrollment target

NCT02038673: Completed Phase 1 study, sponsored by Astellas Pharma.

NCT02038673 is a Phase 1 study that has completed, run by Astellas Pharma. The registered enrollment target is 86 participants, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% higher). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT02038673, a Phase 1 study, has completed, sponsored by Astellas Pharma.

COMPLETED
Registry status
Phase 1
Development phase
86 participants
Enrollment target

Study Summary

The objectives of this study are to determine the tolerability, safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of oral ASP5878 in participants with solid tumors.

Primary Outcome

Until one of the discontinuation criteria is met.

Interventions

  • DRUG ASP5878

Trial Details

FieldValue
Enrollment Target 86 participants
Start Date 2013-11-05
Est. Completion 2017-07-19
Phase Phase 1
Astellas Pharma

165 total trials

What the finished NCT02038673 record still lists

NCT02038673 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 86 participants, a relatively small participant target, above the 60-participant average among 29,502 other Phase 1 trials with a reported enrollment target (43% higher).

The record links to 0 conditions, and to 1 intervention - of which ASP5878 is the first listed.

NCT02038673 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT02038673 about?

NCT02038673 is a clinical study titled "An Open-label Phase I Study of Orally Available Novel Small-molecule Fibroblast Growth Factor Receptors (FGFR) 1,2,3 and 4 Inhibitor, ASP5878 at Single and Multiple Doses in Patients With Solid Tumors". The objectives of this study are to determine the tolerability, safety, pharmacokinetics (PK), pharmacodynamics (PD), and efficacy of oral ASP5878 in participants with solid tumors.

What is the current status of trial NCT02038673?

This trial is currently completed. It is a Phase 1 study. The enrollment target is 86 participants. The study started on 2013-11-05. Estimated completion is 2017-07-19.

What interventions are being tested in trial NCT02038673?

The interventions under investigation include: ASP5878 (DRUG).

Who is sponsoring clinical trial NCT02038673?

This trial is sponsored by Astellas Pharma, which has 165 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT02038673's enrollment target sits among peer trials

86 652nd of 2000 higher than 1,345 of 2,000 other Phase 1 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT02038673, the US trial registry maintained by the National Library of Medicine. NCT02038673 (small enrollment · none site footprint · completed) retrieved and formatted by PlainTrial, see methodology.