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NCT07560150 · ClinicalTrials.gov registry record · Phase 2

Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers

A Phase 2 study, sponsored by Amphastar Pharmaceuticals.

Recruiting
Registry status
Phase 2
Development phase
60
Enrollment target

NCT07560150: Recruiting Phase 2 study, sponsored by Amphastar Pharmaceuticals.

NCT07560150 is a Phase 2 study that is actively recruiting participants, run by Amphastar Pharmaceuticals. The registered enrollment target is 60 participants, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower). According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07560150, a Phase 2 study, is actively recruiting participants, sponsored by Amphastar Pharmaceuticals.

RECRUITING
Registry status
Phase 2
Development phase
60 participants
Enrollment target

Study Summary

This study is a randomized, double-blinded, two-treatment, two-period, two-sequence crossover pivotal Biosimilar study. The purpose of this study is to establish pharmacokinetic (PK) and pharmacodynamic (PD) biosimilarity of proposed biosimilar I004 and the US-approved NovoLog.

Primary Outcome

Pharmacokinetic (PK) blood samples will be collected from 60 minutes before dose through 12 hours post-dose. Serum will be isolated for analyzing the concentrations of Insulin Aspart

Interventions

  • DRUG I004
  • DRUG NovoLog

Trial Details

FieldValue
Enrollment Target 60 participants
Start Date 2026-04-06
Est. Completion 2026-06
Phase Phase 2
Amphastar Pharmaceuticals

21 total trials

What NCT07560150 shows while recruiting

NCT07560150 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 60 participants, a relatively small participant target, below the 133-participant average among 30,622 other Phase 2 trials with a reported enrollment target (55% lower).

The record links to 0 conditions, and to 2 interventions - of which I004 is the first listed.

NCT07560150 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07560150 about?

NCT07560150 is a clinical study titled "Comparison of the Pharmacokinetics (PK) and Pharmacodynamics (PD) Biosimilarity of Proposed Biosimilar/Interchangeable Rapid-Acting Insulin Aspart (I004) and NovoLog® After Single-Dose Subcutaneous Administration to Healthy Volunteers". This study is a randomized, double-blinded, two-treatment, two-period, two-sequence crossover pivotal Biosimilar study. The purpose of this study is to establish pharmacokinetic (PK) and pharmacodynamic (PD) biosimilarity of proposed biosimilar I004 and the US-approved NovoLog.

What is the current status of trial NCT07560150?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 60 participants. The study started on 2026-04-06. Estimated completion is 2026-06.

What interventions are being tested in trial NCT07560150?

The interventions under investigation include: I004 (DRUG), NovoLog (DRUG).

Who is sponsoring clinical trial NCT07560150?

This trial is sponsored by Amphastar Pharmaceuticals, which has 21 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07560150's enrollment target sits among peer trials

60 1027th of 2000 higher than 868 of 2,000 other Phase 2 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 2 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07560150, the US trial registry maintained by the National Library of Medicine. NCT07560150 (small enrollment · none site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.