Aeglea Biotherapeutics
Aeglea Biotherapeutics sponsors 7 registered US clinical trials on ClinicalTrials.gov, none currently recruiting, and 6 completed. 1 of these trials are in Phase 3-4 (later-stage) and 6 in Phase 1-2 (earlier-stage). The most-studied condition in this pipeline is Arginase I Deficiency, with 1 trials.
Trial Pipeline
7 total, page 1 of 1
A Multiple Ascending Dose Study of ACN00177 (Pegtarviliase) in Subjects With CBS Deficiency
NCT05154890
Efficacy and Safety of Pegzilarginase in Patients With Arginase 1 Deficiency
NCT03921541
Pegzilarginase and Pembrolizumab for Extensive Disease Small Cell Lung Cancer
NCT03371979
A Study of AEB1102 (Pegzilarginase) in Patients With Arginase I Deficiency
NCT03378531
A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS
NCT02732184
A Phase 1/2 Study of AEB1102 in Patients With Arginase I Deficiency
NCT02488044
A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With Advanced Solid Tumors
NCT02561234
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
| Phase 2 | 2 |
| Phase 3 | 1 |
Therapeutic Areas
What the Pipeline for Aeglea Biotherapeutics Shows
According to the ClinicalTrials.gov registry, Aeglea Biotherapeutics is linked to 7 US clinical trials across every stage of research activity. Of those, 0 studies are currently recruiting, about 0% of the sponsor's indexed portfolio, and 6 are already marked complete, representing roughly 86% of the total.
The phase mix for Aeglea Biotherapeutics reports 1 late-stage studies (Phase 3 and Phase 4 combined) and 6 earlier-phase studies (Phase 1 and Phase 2).
The top therapeutic focus area indexed for Aeglea Biotherapeutics is Arginase I Deficiency with 1 linked trial, and 1 other condition area appear in the top list above.
How to read these pipeline numbers
Recruiting share is one of the more practical signals here: it reflects how much of a sponsor's research is presently open to new participants, while the completed share indicates the depth of finished work that has already contributed registry results. Both counts come directly from the public ClinicalTrials.gov dataset and are refreshed on the registry side; this page mirrors the latest data pull without altering it.
A portfolio weighted toward Phase 3 usually reflects an organization advancing candidates toward regulatory review, where the research centers on comparative efficacy and broader safety across larger populations. A heavier Phase 1 and Phase 2 tilt generally indicates exploratory work, safety, dosing, and early signal detection, and is common among research-forward sponsors that seed many early programs. Phase 4 entries, when present, track interventions already in real-world use and typically focus on long-term safety, effectiveness across subgroups, or formulation comparisons.
That distribution is a quick read of where the organization concentrates its research attention; it does not imply product availability, market share, or any clinical endorsement. All numbers on this page come from ClinicalTrials.gov maintained by the National Library of Medicine, and counts can shift as new studies are registered or existing ones update their status. This information is provided for reference and educational purposes only, not as medical, investment, or regulatory advice, verify current details directly with ClinicalTrials.gov before relying on any figure here.
Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial from this sponsor, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.