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NCT02732184 · ClinicalTrials.gov registry record · Phase 2

A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS

A Phase 2 study, sponsored by Aeglea Biotherapeutics.

Completed
Registry status
Phase 2
Development phase
29
Enrollment target

NCT02732184 is a Phase 2 study that has completed, run by Aeglea Biotherapeutics. The registered enrollment target is 29 participants.

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The verdict

NCT02732184, a Phase 2 study, has completed, sponsored by Aeglea Biotherapeutics.

COMPLETED
Registry status
Phase 2
Development phase
29 participants
Enrollment target

Study Summary

This is the first study of the safety of increasing dose levels of AEB1102 in patients with Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome. The study will also evaluate the amounts of AEB1102 in blood, the effects of AEB1102 on blood amino acid levels and the antitumor effects of AEB1102.

Interventions

  • DRUG Co-ArgI-PEG modified human arginase I

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2016-08
Est. Completion 2017-12
Phase Phase 2

Sponsor

Aeglea Biotherapeutics

7 total trials

What the Registry Record Tells You About NCT02732184

The ClinicalTrials.gov registry entry for NCT02732184 describes a study currently listed as completed, categorized as Phase 2. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Aeglea Biotherapeutics, which has 7 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 1 intervention - of which Co-ArgI-PEG modified human arginase I is the first listed.

NCT02732184 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT02732184 about?

NCT02732184 is a clinical study titled "A Multiple Dose, Dose Escalation Trial of AEB1102 in Patients With AML or MDS". This is the first study of the safety of increasing dose levels of AEB1102 in patients with Relapsed or Refractory Acute Myeloid Leukemia or Myelodysplastic Syndrome. The study will also evaluate the amounts of AEB1102 in blood, the effects of AEB1102 on blood amino acid levels and the antitumor eff...

What is the current status of trial NCT02732184?

This trial is currently completed. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2016-08. Estimated completion is 2017-12.

What interventions are being tested in trial NCT02732184?

The interventions under investigation include: Co-ArgI-PEG modified human arginase I (DRUG).

Who is sponsoring clinical trial NCT02732184?

This trial is sponsored by Aeglea Biotherapeutics, which has 7 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.