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ClinicalTrials.gov official registry

Therapy-Related Acute Myeloid Leukemia clinical trials

All 11 indexed Therapy-Related Acute Myeloid Leukemia trials have closed enrollment.

11 US clinical trials ·

Therapy-Related Acute Myeloid Leukemia is the subject of 11 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 0 are in Phase 3-4 (later-stage) and 11 in Phase 1-2 (earlier-stage). The most active sponsor is M.D. Anderson Cancer Center, running 4 of these trials.

The research picture

Therapy-Related Acute Myeloid Leukemia has 11 registered US clinical trials; none are currently listed as recruiting, so most are completed or in follow-up.

0
recruiting participants now
0%
of trials open to enrollment
0
in Phase 3–4 (later-stage)
4
top sponsor: M.D. Anderson Cancer Center
Phase 14Phase 27

Active & Recent Trials

11 total, page 1 of 1

ACTIVE NOT RECRUITING Phase 2 100 participants

Venetoclax and Azacitidine for the Treatment of Acute Myeloid Leukemia in the Post-Transplant Setting

M.D. Anderson Cancer Center

NCT04128501

ACTIVE NOT RECRUITING Phase 1 53 participants

Pevonedistat, Cytarabine, and Idarubicin in Treating Patients With Acute Myeloid Leukemia

University of Southern California

NCT03330821

ACTIVE NOT RECRUITING Phase 2 50 participants

AZA + Venetoclax as Maintenance Therapy in Patients With AML in Remission

M.D. Anderson Cancer Center

NCT04062266

ACTIVE NOT RECRUITING Phase 1 30 participants

Pevonedistat and Decitabine in Treating Patients With High Risk Acute Myeloid Leukemia

City of Hope Medical Center

NCT03009240

ACTIVE NOT RECRUITING Phase 2 21 participants

CPX-351 for the Treatment of Secondary Acute Myeloid Leukemia in Patients Younger Than 60 Years Old

Roswell Park Cancer Institute

NCT04269213

COMPLETED Phase 2 165 participants

Decitabine With or Without Bortezomib in Treating Older Patients With Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT01420926

COMPLETED Phase 2 150 participants

Nivolumab and Azacitidine With or Without Ipilimumab in Treating Patients With Refractory/Relapsed or Newly Diagnosed Acute Myeloid Leukemia

M.D. Anderson Cancer Center

NCT02397720

COMPLETED Phase 2 61 participants

Combination Chemotherapy and Dasatinib in Treating Patients With Newly Diagnosed Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT01238211

COMPLETED Phase 1 54 participants

Natural Killer Cells Before and After Donor Stem Cell Transplant in Treating Patients With Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelogenous Leukemia

M.D. Anderson Cancer Center

NCT01904136

COMPLETED Phase 2 54 participants

Sorafenib Tosylate and Chemotherapy in Treating Older Patients With Acute Myeloid Leukemia

National Cancer Institute (NCI)

NCT01253070

COMPLETED Phase 1 13 participants

Pacritinib and Chemotherapy in Treating Patients With Acute Myeloid Leukemia and FLT3 Mutations

Bhavana Bhatnagar

NCT02323607

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 7

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Therapy-Related Acute Myeloid Leukemia Trial Landscape

11 indexed Therapy-Related Acute Myeloid Leukemia studies · 0 recruiting (0%).

Phase mix: 0 late (III/IV) vs 11 early (I/II).

Top sponsor: M.D. Anderson Cancer Center (4 trials), 5 others listed. 11 shown below, recruiting first.

How to read this condition's trial landscape

That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation, eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Therapy-Related Acute Myeloid Leukemia?

PlainTrial tracks 11 US clinical trials for Therapy-Related Acute Myeloid Leukemia, of which 0 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Therapy-Related Acute Myeloid Leukemia?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

Verify with NIH →

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page aggregates every registered trial for this condition, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.