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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Recurrent Grade 2 Follicular Lymphoma: early-phase trial registry

2 of 12 indexed Recurrent Grade 2 Follicular Lymphoma trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,429 of 28,707 conditions by registered trial count.

12 US clinical trials · 2 currently recruiting · #1,429 of 28,707 conditions by registered trial count

Recurrent Grade 2 Follicular Lymphoma: 12 US clinical trials tracked, 2 recruiting.

Recurrent Grade 2 Follicular Lymphoma is the subject of 12 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 12 in Phase 1-2 (earlier-stage). The most active sponsor is City of Hope Medical Center, running 4 of these trials.

Enrollment posture brief

Registry condition recurrent-grade-2-follicular-lymphoma

OPEN 2 | RECR 17% | LATE 0 | EARLY 12 | RANK #1429 | SPON 4

Nearest open-share peer: Acute Renal Failure (17% recruiting · 6 trials)

Acute Myeloid Leukemia in Re41.7%Adenocarcinoma of the Rectum41.7%Recurrent Grade 2 Follic (th…17%Adherence, Patient16.7%Accelerated Phase Chronic My0%
Open-enrollment share among volume-matched conditions near Recurrent Grade 2 Follicular Lymphoma

Recurrent Grade 2 Follicular Lymphoma lists 2 open slots (17% of 12 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Recurrent Grade 2 Follicular Lymphoma on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Recurrent Grade 2 Follicular Lymphoma is recruiting below its size-band peers.

    2 of 12 indexed trials (16.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Recurrent Grade 2 Follicular Lymphoma research.

    City of Hope Medical Center accounts for 4 of 12 trials (33.3%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most Recurrent Grade 2 Follicular Lymphoma trials plan to enrol fewer than 100 people.

    Median target enrolment is 38 among the 12 trials that report a genuine target (sentinel values excluded). 12 of those (100%) plan for fewer than 100 participants.

  4. Recurrent Grade 2 Follicular Lymphoma research is mostly interventional.

    12 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 17Phase 25

Open and recent trials

12 total, page 1 of 1

RECRUITING Phase 2 41 participants

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

City of Hope Medical Center

NCT06453044

RECRUITING Phase 1 37 participants

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT06859008

ACTIVE NOT RECRUITING Phase 2 53 participants

Rituximab and Pembrolizumab With or Without Lenalidomide in Treating Patients With Relapsed Follicular Lymphoma and Diffuse Large B-Cell Lymphoma

M.D. Anderson Cancer Center

NCT02446457

ACTIVE NOT RECRUITING Phase 1 52 participants

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.

City of Hope Medical Center

NCT03150329

ACTIVE NOT RECRUITING Phase 1 48 participants

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

Kami Maddocks, MD

NCT01479842

ACTIVE NOT RECRUITING Phase 2 41 participants

Ibrutinib in Treating Patients With Relapsed or Refractory Follicular Lymphoma

National Cancer Institute (NCI)

NCT01849263

ACTIVE NOT RECRUITING Phase 1 36 participants

Nivolumab and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

David Bond, MD

NCT03015896

ACTIVE NOT RECRUITING Phase 1 21 participants

Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma

National Cancer Institute (NCI)

NCT02520791

ACTIVE NOT RECRUITING Phase 2 20 participants

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

University of Washington

NCT04205409

ACTIVE NOT RECRUITING Phase 1 8 participants

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT01318317

COMPLETED Phase 1 38 participants

Iodine I 131 Tositumomab and Fludarabine Phosphate in Treating Older Patients Who Are Undergoing an Autologous or Syngeneic Stem Cell Transplant for Relapsed or Refractory Non-Hodgkin's Lymphoma

Fred Hutchinson Cancer Center

NCT00110071

COMPLETED Phase 2 28 participants

Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation

National Cancer Institute (NCI)

NCT00058305

Phase Distribution

PhaseTrial count
Phase 1 7
Phase 2 5

Named interventions

Most-linked intervention names on Recurrent Grade 2 Follicular Lymphoma records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Laboratory Biomarker Analysis Other
6 trials
Nivolumab Biological
2 trials
Lenalidomide Drug
2 trials
laboratory biomarker analysis Other
2 trials
Computed Tomography Procedure
2 trials
Biospecimen Collection Procedure
2 trials
Pembrolizumab Biological
2 trials
iodine I 131 tositumomab Radiation
1 trials

US sites by state

Facility locations filed on Recurrent Grade 2 Follicular Lymphoma trials. A trial with sites in several states counts in each.

California 5 trials
Ohio 4 trials
Washington 2 trials
Texas 2 trials
Missouri 2 trials
Florida 2 trials
Wisconsin 1 trials
Pennsylvania 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Recurrent Grade 2 Follicular Lymphoma page

12 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 2 Recurrent Grade 2 Follicular Lymphoma trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • City of Hope Medical Center sponsors the most Recurrent Grade 2 Follicular Lymphoma trials on record, review their full trial history before evaluating a specific study. See City of Hope Medical Center's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Recurrent Grade 2 Follicular Lymphoma condition card totals 12 registered trials; most-linked intervention Laboratory Biomarker Analysis; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.