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2026 data Public-data reference. official source

Recurrent Grade 1 Follicular Lymphoma

Open-data reference.

12 US clinical trials · 2 currently recruiting

Active & Recent Trials

RECRUITING Phase 2 41 participants

Mosunetuzumab and Polatuzumab Vedotin for the Treatment of Patients With Relapsed or Refractory Grade 1-3a Follicular Lymphoma

City of Hope Medical Center

NCT06453044

RECRUITING Phase 1 37 participants

Zanubrutinib in Combination With Sonrotoclax for the Treatment of Underrepresented Ethnic and Racial Minorities With Relapsed or Refractory B-cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT06859008

ACTIVE NOT RECRUITING Phase 2 53 participants

Rituximab and Pembrolizumab With or Without Lenalidomide in Treating Patients With Relapsed Follicular Lymphoma and Diffuse Large B-Cell Lymphoma

M.D. Anderson Cancer Center

NCT02446457

ACTIVE NOT RECRUITING Phase 1 52 participants

Pembrolizumab and Vorinostat in Patients With Relapsed or Refractory DLBCL, FCL or HL.

City of Hope Medical Center

NCT03150329

ACTIVE NOT RECRUITING Phase 1 48 participants

Rituxan/Bendamustine/PCI-32765 in Relapsed DLBCL, MCL, or Indolent Non-Hodgkin's Lymphoma

Kami Maddocks, MD

NCT01479842

ACTIVE NOT RECRUITING Phase 2 41 participants

Ibrutinib in Treating Patients With Relapsed or Refractory Follicular Lymphoma

National Cancer Institute (NCI)

NCT01849263

ACTIVE NOT RECRUITING Phase 1 36 participants

Nivolumab and Lenalidomide in Treating Patients With Relapsed or Refractory Non-Hodgkin or Hodgkin Lymphoma

David Bond, MD

NCT03015896

ACTIVE NOT RECRUITING Phase 1 21 participants

Anti-ICOS Monoclonal Antibody MEDI-570 in Treating Patients With Relapsed or Refractory Peripheral T-cell Lymphoma Follicular Variant or Angioimmunoblastic T-cell Lymphoma

National Cancer Institute (NCI)

NCT02520791

ACTIVE NOT RECRUITING Phase 2 20 participants

Nivolumab for Relapsed, Refractory, or Detectable Disease Post Chimeric Antigen Receptor T-cell Treatment in Patients With Hematologic Malignancies

University of Washington

NCT04205409

ACTIVE NOT RECRUITING Phase 1 8 participants

Genetically Engineered Lymphocyte Therapy After Peripheral Blood Stem Cell Transplant in Treating Patients With High-Risk, Intermediate-Grade, B-cell Non-Hodgkin Lymphoma

City of Hope Medical Center

NCT01318317

COMPLETED Phase 1 38 participants

Iodine I 131 Tositumomab and Fludarabine Phosphate in Treating Older Patients Who Are Undergoing an Autologous or Syngeneic Stem Cell Transplant for Relapsed or Refractory Non-Hodgkin's Lymphoma

Fred Hutchinson Cancer Center

NCT00110071

COMPLETED Phase 2 28 participants

Bryostatin 1 Plus Vincristine in Treating Patients With Progressive or Relapsed Non-Hodgkin's Lymphoma After Bone Marrow or Stem Cell Transplantation

National Cancer Institute (NCI)

NCT00058305

Phase Distribution

PhaseTrial count
Early Phase 1 7
Phase 2 5

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

Reading the Recurrent Grade 1 Follicular Lymphoma Trial Landscape

ClinicalTrials.gov lists 12 US studies indexed under Recurrent Grade 1 Follicular Lymphoma, and 2 of those are currently open to recruitment — roughly 17% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.

The phase distribution for Recurrent Grade 1 Follicular Lymphoma shows 0 late-stage studies (Phase 3 and Phase 4 combined) alongside 12 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.

Top sponsor activity for Recurrent Grade 1 Follicular Lymphoma is led by City of Hope Medical Center with 4 indexed trials, alongside 6 other organizations in the top contributor list. The list on this page surfaces up to 12 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.

Frequently Asked Questions

How many clinical trials are there for Recurrent Grade 1 Follicular Lymphoma?

PlainTrial tracks 12 US clinical trials for Recurrent Grade 1 Follicular Lymphoma, of which 2 are currently recruiting participants. Data sourced from ClinicalTrials.gov.

How do I find a recruiting trial for Recurrent Grade 1 Follicular Lymphoma?

Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.

Is this data current?

Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.

Related

Data sourced from official U.S. government datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.

Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2024 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.

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