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Proliferative Diabetic Retinopathy: early-phase trial registry
A small indexed set (6 trials) with no open enrollment listed right now.
Corpus placement: #2,866 of 28,707 conditions by registered trial count.
6 US clinical trials · none currently recruiting · #2,866 of 28,707 conditions by registered trial count
Proliferative Diabetic Retinopathy: 6 US clinical trials tracked, none currently recruiting.
Proliferative Diabetic Retinopathy is the subject of 6 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 1 are in Phase 3-4 (later-stage) and 5 in Phase 1-2 (earlier-stage). The most active sponsor is Charles C Wykoff, PhD, MD, running 1 of these trials.
Enrollment posture brief
Registry condition proliferative-diabetic-retinopathy
OPEN 0 | RECR 0% | LATE 1 | EARLY 5 | RANK #2866 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)
Proliferative Diabetic Retinopathy has no open enrollment in this registry pull (6 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Proliferative Diabetic Retinopathy on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Proliferative Diabetic Retinopathy is recruiting below its size-band peers.
0 of 6 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Proliferative Diabetic Retinopathy research.
Charles C Wykoff, PhD, MD accounts for 1 of 6 trials (16.7%). 6 distinct sponsors appear on at least one study for this condition label.
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Typical Proliferative Diabetic Retinopathy enrolment sits around 114 participants.
Median target enrolment is 114 among the 6 trials that report a genuine target (sentinel values excluded). 3 of those (50%) plan for fewer than 100 participants.
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Proliferative Diabetic Retinopathy research is mostly interventional.
6 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Indexed trials (enrollment closed)
6 total, page 1 of 1
Phase 2 Spectra Study to Evaluate the Safety and Efficacy of OPL-0401 in Patients With Diabetic Retinopathy
Valo Health
NCT05393284
Study of Efficacy and Safety of Brolucizumab Versus Panretinal Photocoagulation Laser in Patients With Proliferative Diabetic Retinopathy
Novartis Pharmaceuticals
NCT04278417
Anti-VEGF vs. Prompt Vitrectomy for VH From PDR
Jaeb Center for Health Research
NCT02858076
Intravitreal Aflibercept for Retinal Non-Perfusion in Proliferative Diabetic Retinopathy
Charles C Wykoff, PhD, MD
NCT02863354
Study to Evaluate Effects of Emixustat Hydrochloride in Subjects With Proliferative Diabetic Retinopathy
Kubota Vision
NCT02753400
Ranibizumab for Treatment of Persistent Diabetic Neovascularization Assessed by Wide-Field Imaging
Rush University Medical Center
NCT00606138
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 4 |
| Phase 3 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Proliferative Diabetic Retinopathy records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Proliferative Diabetic Retinopathy trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Proliferative Diabetic Retinopathy page
6 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- No Proliferative Diabetic Retinopathy trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
- Charles C Wykoff, PhD, MD sponsors the most Proliferative Diabetic Retinopathy trials on record, review their full trial history before evaluating a specific study. See Charles C Wykoff, PhD, MD's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Proliferative Diabetic Retinopathy condition card totals 6 registered trials; most-linked intervention Laser photocoagulation; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.