Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Patent Foramen Ovale: full-pipeline trial registry
2 of 8 indexed Patent Foramen Ovale trials are currently recruiting.
Corpus placement: #2,176 of 28,707 conditions by registered trial count.
8 US clinical trials · 2 currently recruiting · #2,176 of 28,707 conditions by registered trial count
Patent Foramen Ovale: 8 US clinical trials tracked, 2 recruiting.
Patent Foramen Ovale is the subject of 8 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University of Oregon, running 2 of these trials.
Enrollment posture brief
Registry condition patent-foramen-ovale
OPEN 2 | RECR 25% | LATE 1 | EARLY 1 | RANK #2176 | SPON 2
Volume-matched condition peers
Nearest open-share peer: Abdominal Pain (25% recruiting · 20 trials)
Patent Foramen Ovale lists 2 open slots (25% of 8 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Patent Foramen Ovale on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Patent Foramen Ovale is recruiting below its size-band peers.
2 of 8 indexed trials (25%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Patent Foramen Ovale research.
University of Oregon accounts for 2 of 8 trials (25%). 7 distinct sponsors appear on at least one study for this condition label.
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Typical Patent Foramen Ovale enrolment sits around 450 participants.
Median target enrolment is 450 among the 8 trials that report a genuine target (sentinel values excluded). 4 of those (50%) plan for fewer than 100 participants.
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Patent Foramen Ovale research is mostly interventional.
6 interventional and 2 observational studies make up this index (75% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
8 total, page 1 of 1
Encore PFO Closure Device - The PerFOrm Trial
Encore Medical
NCT05537753
Early Feasibility Study (EFS) Evaluating Percutaneous Repair of the Atrial Septum With a Novel PFO Occluder: The PROTEA-PFO Study
Recross Cardio
NCT07172464
AMPLATZER PFO Occluder Post Approval Study
Abbott Medical Devices
NCT03309332
Comparing PFO Outcomes of the Occlutech Flex II PFO Occluder to Standard of Care PFO Occlusion
Occlutech International AB
NCT05069558
Patent Foramen Ovale in Cryptogenic Stroke Study
Columbia University
NCT00697151
Is Blood Flow Through IPAVA and PFO Related to Breath-hold and SCUBA Diving-induced Pulmonary Hypertension?
University of Oregon
NCT03945643
Comorbidities Associated With Migraine and Patent Foramen Ovale (CAMP)
Swedish Medical Center
NCT01257880
Does Patent Foramen Ovale Size Matter in Men and Women
University of Oregon
NCT03904277
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Patent Foramen Ovale records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Patent Foramen Ovale trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Patent Foramen Ovale page
8 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Patent Foramen Ovale trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- University of Oregon sponsors the most Patent Foramen Ovale trials on record, review their full trial history before evaluating a specific study. See University of Oregon's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Patent Foramen Ovale condition card totals 8 registered trials; most-linked intervention Standard of Care PFO Closure Device; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.