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ClinicalTrials.gov 2 recruiting now early-phase tilt small index

Pain, Orofacial: early-phase trial registry

2 of 2 indexed Pain, Orofacial trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #7,188 of 28,707 conditions by registered trial count.

2 US clinical trials · 2 currently recruiting · #7,188 of 28,707 conditions by registered trial count

Pain, Orofacial: 2 US clinical trials tracked, 2 recruiting.

Pain, Orofacial is the subject of 2 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is University of Colorado, Denver, running 2 of these trials.

Enrollment posture brief

Registry condition pain-orofacial

OPEN 2 | RECR 100% | LATE 0 | EARLY 1 | RANK #7188 | SPON 2

Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)

Pain, Orofacial (this)100%Ablation80%ACL Reconstruction80%Abuse, Drug60%Acceptability60%
Open-enrollment share among volume-matched conditions near Pain, Orofacial

Pain, Orofacial lists 2 open slots (100% of 2 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Pain, Orofacial on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Pain, Orofacial is recruiting above its size-band peers.

    2 of 2 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

Phase 11

Phase Distribution

PhaseTrial count
Phase 1 1

Top Sponsors

Named interventions

Most-linked intervention names on Pain, Orofacial records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Ibuprofen 200 mg Drug
1 trials
Ibuprofen 200 mg and acetaminphen 650 mg Drug
1 trials
Device: 0.016" Ormco 35oC NiTi orthodontic archwire Device
1 trials
Device: 0.016" Ormco 27oC NiTi orthodontic archwire Device
1 trials
3M Unitek 0.016 orthodontic archwire Device
1 trials
Placebo oral tablet Drug
1 trials

US sites by state

Facility locations filed on Pain, Orofacial trials. A trial with sites in several states counts in each.

Colorado 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Pain, Orofacial page

2 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Pain, Orofacial condition card totals 2 registered trials; most-linked intervention Ibuprofen 200 mg; top US site state Colorado. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.