Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Metastatic Hormone-sensitive Prostate Cancer: early-phase trial registry

4 of 6 indexed Metastatic Hormone-sensitive Prostate Cancer trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,866 of 28,707 conditions by registered trial count.

6 US clinical trials · 4 currently recruiting · #2,866 of 28,707 conditions by registered trial count

Metastatic Hormone-sensitive Prostate Cancer: 6 US clinical trials tracked, 4 recruiting.

Metastatic Hormone-sensitive Prostate Cancer is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is Bayer, running 2 of these trials.

Enrollment posture brief

Registry condition metastatic-hormone-sensitive-prostate-cancer

OPEN 4 | RECR 67% | LATE 1 | EARLY 4 | RANK #2866 | SPON 2

Nearest open-share peer: Adenocarcinoma of Lung (67% recruiting · 6 trials)

Metastatic Hormone-sensi (th…67%Acute Hypoxemic Respiratory 66.7%Abdominal Aortic Aneurysms50%Acupuncture50%Acute Lymphoblastic Leukemia50%
Open-enrollment share among volume-matched conditions near Metastatic Hormone-sensitive Prostate Cancer

Metastatic Hormone-sensitive Prostate Cancer lists 4 open slots (67% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Metastatic Hormone-sensitive Prostate Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Metastatic Hormone-sensitive Prostate Cancer is recruiting above its size-band peers.

    4 of 6 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Metastatic Hormone-sensitive Prostate Cancer research.

    Bayer accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Typical Metastatic Hormone-sensitive Prostate Cancer enrolment sits around 277 participants.

    Median target enrolment is 277 among the 6 trials that report a genuine target (sentinel values excluded). 0 of those (0%) plan for fewer than 100 participants.

  4. Metastatic Hormone-sensitive Prostate Cancer research is mostly interventional.

    5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 11Phase 23Phase 31

Open and recent trials

6 total, page 1 of 1

RECRUITING 1,400 participants

A Study to Learn About Real-world Utilization and Outcomes of Darolutamide and Other Androgen Receptor Pathway Inhibitors (ARPIs) for Newly Diagnosed Metastatic Hormone-sensitive Prostate Cancer (de Novo mHSPC) in US Urology Clinics

Bayer

NCT07406282

RECRUITING Phase 1 277 participants

A Study of JNJ-78278343 in Combination With Either JNJ-63723283 (Cetrelimab), Taxane Chemotherapy, or Androgen Receptor Pathway Inhibitors for Metastatic Prostate Cancer

Janssen Research & Development

NCT05818683

RECRUITING Phase 2 218 participants

A Phase 2 Study to Evaluate the Effects of ASP5541 in Participants With Prostate Cancer

Astellas Pharma Global Development

NCT07005154

RECRUITING Phase 2 150 participants

An Open-label Study of JSB462 (Luxdegalutamide) in Combination With Abiraterone in Adult Male Patients With Metastatic Hormone-sensitive Prostate Cancer (mHSPC)

Novartis Pharmaceuticals

NCT06991556

ACTIVE NOT RECRUITING Phase 3 1,251 participants

Efficacy and Safety of Pembrolizumab (MK-3475) Plus Enzalutamide Plus Androgen Deprivation Therapy (ADT) Versus Placebo Plus Enzalutamide Plus ADT in Participants With Metastatic Hormone-Sensitive Prostate Cancer (mHSPC) (MK-3475-991/KEYNOTE-991)

Merck Sharp & Dohme

NCT04191096

ACTIVE NOT RECRUITING Phase 2 223 participants

A Study to Learn How Well Darolutamide Administered Together With Androgen Deprivation Therapy (ADT) Works in Men With Metastatic Hormone-sensitive Prostate Cancer. Results Will be Compared With ADT Alone From a Previously Conducted Study.

Bayer

NCT05059236

Phase Distribution

PhaseTrial count
Phase 1 1
Phase 2 3
Phase 3 1

Named interventions

Most-linked intervention names on Metastatic Hormone-sensitive Prostate Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Enzalutamide Drug
3 trials
Apalutamide Drug
2 trials
ADT Other
1 trials
Darolutamide (BAY1841788, Nubeqa) Drug
1 trials
Adrenocorticotropic hormone Drug
1 trials
ASP5541 Drug
1 trials
Androgen Deprivation Therapy (ADT) Drug
1 trials
JSB462 Drug
1 trials

US sites by state

Facility locations filed on Metastatic Hormone-sensitive Prostate Cancer trials. A trial with sites in several states counts in each.

New York 3 trials
Georgia 3 trials
California 3 trials
South Carolina 2 trials
Pennsylvania 2 trials
Ohio 2 trials
New Mexico 2 trials
Nebraska 2 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Metastatic Hormone-sensitive Prostate Cancer page

6 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 4 Metastatic Hormone-sensitive Prostate Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • Bayer sponsors the most Metastatic Hormone-sensitive Prostate Cancer trials on record, review their full trial history before evaluating a specific study. See Bayer's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Metastatic Hormone-sensitive Prostate Cancer condition card totals 6 registered trials; most-linked intervention Enzalutamide; top US site state New York. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.