Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Leigh Disease clinical trials
2 of 2 indexed Leigh Disease trials are currently recruiting.
Corpus placement: #7,188 of 28,707 conditions by registered trial count.
2 US clinical trials · 2 currently recruiting · #7,188 of 28,707 conditions by registered trial count
Leigh Disease: 2 US clinical trials tracked, 2 recruiting.
Leigh Disease is the subject of 2 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. The most active sponsor is National Human Genome Research Institute (NHGRI), running 1 of these trials.
Enrollment posture brief
Registry condition leigh-disease
OPEN 2 | RECR 100% | LATE 0 | EARLY 0 | RANK #7188 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Aortic Arch Aneurysm (100% recruiting · 5 trials)
Leigh Disease lists 2 open slots (100% of 2 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Leigh Disease on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Leigh Disease is recruiting above its size-band peers.
2 of 2 indexed trials (100%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
2 total, page 1 of 1
The NIH MINI Study: Metabolism, Infection, and Immunity in Inborn Errors of Metabolism
National Human Genome Research Institute (NHGRI)
NCT01780168
The International Registry for Leigh Syndrome
The University of Texas Health Science Center, Houston
NCT03137355
Phase Distribution
Phase data not available
Top Sponsors
US sites by state
Facility locations filed on Leigh Disease trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Leigh Disease page
2 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Leigh Disease trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- National Human Genome Research Institute (NHGRI) sponsors the most Leigh Disease trials on record, review their full trial history before evaluating a specific study. See National Human Genome Research Institute (NHGRI)'s trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Leigh Disease condition card totals 2 registered trials; top US site state Texas. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.