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ClinicalTrials.gov 6 recruiting now early-phase tilt small index

High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements: early-phase trial registry

6 of 9 indexed High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #1,916 of 28,707 conditions by registered trial count.

9 US clinical trials · 6 currently recruiting · #1,916 of 28,707 conditions by registered trial count

High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements: 9 US clinical trials tracked, 6 recruiting.

High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements is the subject of 9 registered US clinical trials on ClinicalTrials.gov, 6 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 9 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 2 of these trials.

Enrollment posture brief

Registry condition high-grade-b-cell-lymphoma-with-myc-and-bcl2-andor-bcl6-rearrangements

OPEN 6 | RECR 67% | LATE 0 | EARLY 9 | RANK #1916 | SPON 2

Nearest open-share peer: Acute Hypoxemic Respiratory Failure (67% recruiting · 6 trials)

High Grade B-Cell Lympho (this)High Grade B-Cell Lympho (th…67%Acute Lymphoblastic Leukemia55.6%Acute Respiratory Distress S55.6%Acute Otitis Media22.2%Acute Heart Failure11.1%
Open-enrollment share among volume-matched conditions near High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements

High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements lists 6 open slots (67% of 9 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements is recruiting above its size-band peers.

    6 of 9 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements research.

    University of Washington accounts for 2 of 9 trials (22.2%). 7 distinct sponsors appear on at least one study for this condition label.

  3. Most High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements trials plan to enrol fewer than 100 people.

    Median target enrolment is 50 among the 9 trials that report a genuine target (sentinel values excluded). 7 of those (77.8%) plan for fewer than 100 participants.

  4. High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements research is mostly interventional.

    9 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 14Phase 25

Open and recent trials

9 total, page 1 of 1

RECRUITING Phase 1 276 participants

Inotuzumab Ozogamicin and Combination Chemotherapy in Treating Patients With Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center

NCT01371630

RECRUITING Phase 2 227 participants

Study Adding Drugs to Usual Treatment for Large B-Cell Lymphoma That Returned or Did Not Respond to Treatment

SWOG Cancer Research Network

NCT05890352

RECRUITING Phase 1 56 participants

Polatuzumab Vedotin and Combination Chemotherapy With or Without Glofitamab for the Treatment of Untreated Aggressive Large B-cell Lymphoma

University of Washington

NCT04231877

RECRUITING Phase 1 50 participants

Testing the Safety of Anti-Cancer Drug, CX-5461 (Pidnarulex), in Treating Lymphoma With Specific Changes in the MYC Gene

National Cancer Institute (NCI)

NCT07069699

RECRUITING Phase 2 24 participants

Loncastuximab Tesirine and Rituximab Followed by DA-EPOCH-R for Treating Patients With High-Risk Diffuse Large B-cell Lymphoma

Joseph Tuscano

NCT05600686

RECRUITING Phase 2 18 participants

Epcoritamab With Dose Adjusted Etoposide, Cyclophosphamide, Vincristine, Doxorubicin, Prednisone and Rituximab (EPOCH-R) for the Treatment of Aggressive B-Cell Non-Hodgkin Lymphoma

University of Washington

NCT07097363

ACTIVE NOT RECRUITING Phase 2 54 participants

Nivolumab With or Without Varlilumab in Treating Patients With Relapsed or Refractory Aggressive B-cell Lymphomas

National Cancer Institute (NCI)

NCT03038672

ACTIVE NOT RECRUITING Phase 2 30 participants

Nivolumab With DA-REPOCH Chemotherapy Regimen in Treating Patients With Aggressive B-Cell Non-Hodgkin's Lymphoma

David Bond, MD

NCT03749018

COMPLETED Phase 1 12 participants

Combination Chemotherapy and TAK-659 as Front-Line Treatment in Treating Patients With High-Risk Diffuse Large B Cell Lymphoma

Northwestern University

NCT03742258

Phase Distribution

PhaseTrial count
Phase 1 4
Phase 2 5

Named interventions

Most-linked intervention names on High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
5 trials
Prednisone Drug
4 trials
Etoposide Drug
3 trials
Computed Tomography Procedure
3 trials
Biospecimen Collection Procedure
3 trials
Rituximab Biological
2 trials
Nivolumab Biological
2 trials
Doxorubicin Hydrochloride Drug
2 trials

US sites by state

Facility locations filed on High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements trials. A trial with sites in several states counts in each.

Illinois 3 trials
Washington 2 trials
Florida 2 trials
California 2 trials
Arizona 2 trials
Texas 1 trials
Ohio 1 trials
Kansas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements page

9 registered trials, 6 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

  • 6 High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
  • University of Washington sponsors the most High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements trials on record, review their full trial history before evaluating a specific study. See University of Washington's trials
  • Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This High Grade B-Cell Lymphoma With MYC and BCL2 and/or BCL6 Rearrangements condition card totals 9 registered trials; most-linked intervention Cyclophosphamide; top US site state Illinois. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.