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ClinicalTrials.gov 4 recruiting now early-phase tilt small index

Heart Failure NYHA Class IV: early-phase trial registry

4 of 6 indexed Heart Failure NYHA Class IV trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #2,866 of 28,707 conditions by registered trial count.

6 US clinical trials · 4 currently recruiting · #2,866 of 28,707 conditions by registered trial count

Heart Failure NYHA Class IV: 6 US clinical trials tracked, 4 recruiting.

Heart Failure NYHA Class IV is the subject of 6 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 2 in Phase 1-2 (earlier-stage). The most active sponsor is University of Washington, running 2 of these trials.

Enrollment posture brief

Registry condition heart-failure-nyha-class-iv

OPEN 4 | RECR 67% | LATE 0 | EARLY 2 | RANK #2866 | SPON 2

Nearest open-share peer: Adenocarcinoma of Lung (67% recruiting · 6 trials)

Heart Failure NYHA Class (th…67%Acute Hypoxemic Respiratory 66.7%Abdominal Aortic Aneurysms50%Acupuncture50%Acute Lymphoblastic Leukemia50%
Open-enrollment share among volume-matched conditions near Heart Failure NYHA Class IV

Heart Failure NYHA Class IV lists 4 open slots (67% of 6 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for Heart Failure NYHA Class IV on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. Heart Failure NYHA Class IV is recruiting above its size-band peers.

    4 of 6 indexed trials (66.7%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates Heart Failure NYHA Class IV research.

    University of Washington accounts for 2 of 6 trials (33.3%). 5 distinct sponsors appear on at least one study for this condition label.

  3. Typical Heart Failure NYHA Class IV enrolment sits around 208 participants.

    Median target enrolment is 208 among the 6 trials that report a genuine target (sentinel values excluded). 3 of those (50%) plan for fewer than 100 participants.

  4. Heart Failure NYHA Class IV research is mostly interventional.

    5 interventional and 1 observational studies make up this index (83.3% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 12

Phase Distribution

PhaseTrial count
Phase 1 2

Top Sponsors

Named interventions

Most-linked intervention names on Heart Failure NYHA Class IV records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

CardioMEMS™ HF System Device
1 trials
Tricuspid Valve Repair (TVR) Procedure
1 trials
Left ventricular assist device (LVAD) Device
1 trials
HF-FamPALhomeCARE Behavioral
1 trials
iPSC-CL Biological
1 trials
Nicotinamide riboside Drug
1 trials
Placebo Other
1 trials

US sites by state

Facility locations filed on Heart Failure NYHA Class IV trials. A trial with sites in several states counts in each.

Washington 2 trials
West Virginia 1 trials
Minnesota 1 trials
Connecticut 1 trials
Colorado 1 trials
California 1 trials
Arizona 1 trials
Arkansas 1 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this Heart Failure NYHA Class IV page

6 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Heart Failure NYHA Class IV condition card totals 6 registered trials; most-linked intervention CardioMEMS™ HF System; top US site state Washington. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.