Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Head and Neck Squamous Cell Cancer: early-phase trial registry
3 of 5 indexed Head and Neck Squamous Cell Cancer trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #3,391 of 28,707 conditions by registered trial count.
5 US clinical trials · 3 currently recruiting · #3,391 of 28,707 conditions by registered trial count
Head and Neck Squamous Cell Cancer: 5 US clinical trials tracked, 3 recruiting.
Head and Neck Squamous Cell Cancer is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 3 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 4 in Phase 1-2 (earlier-stage). The most active sponsor is VLP Therapeutics, running 1 of these trials.
Enrollment posture brief
Registry condition head-and-neck-squamous-cell-cancer
OPEN 3 | RECR 60% | LATE 0 | EARLY 4 | RANK #3391 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute Kidney Injury (AKI) (60% recruiting · 5 trials)
Head and Neck Squamous Cell Cancer lists 3 open slots (60% of 5 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Head and Neck Squamous Cell Cancer on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Head and Neck Squamous Cell Cancer is recruiting above its size-band peers.
3 of 5 indexed trials (60%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Head and Neck Squamous Cell Cancer research.
VLP Therapeutics accounts for 1 of 5 trials (20%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical Head and Neck Squamous Cell Cancer enrolment sits around 240 participants.
Median target enrolment is 240 among the 5 trials that report a genuine target (sentinel values excluded). 1 of those (20%) plan for fewer than 100 participants.
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Head and Neck Squamous Cell Cancer research is mostly interventional.
4 interventional and 1 observational studies make up this index (80% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
5 total, page 1 of 1
Study of XB010 in Subjects With Solid Tumors
Exelixis
NCT06545331
A Study to Evaluate the Safety and Efficacy of A2B395, an Allogeneic Logic-gated CAR T, in Participants With Solid Tumors That Express EGFR and Have Lost HLA-A*02 Expression
A2 Biotherapeutics
NCT06682793
Intratumoral Delivery of Viral Replicon (saRNA) Particles Expressing IL-12 in Head and Neck Cancer
VLP Therapeutics
NCT06736379
Head and Neck Cancer Screening and Serum Repository
University of Arkansas
NCT00592371
A Study of LGK974 in Patients With Malignancies Dependent on Wnt Ligands
Novartis Pharmaceuticals
NCT01351103
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Head and Neck Squamous Cell Cancer records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Head and Neck Squamous Cell Cancer trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Head and Neck Squamous Cell Cancer page
5 registered trials, 3 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 3 Head and Neck Squamous Cell Cancer trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- VLP Therapeutics sponsors the most Head and Neck Squamous Cell Cancer trials on record, review their full trial history before evaluating a specific study. See VLP Therapeutics's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Head and Neck Squamous Cell Cancer condition card totals 5 registered trials; most-linked intervention PDR001; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.