Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Familial Chylomicronemia Syndrome: later-stage trial registry
A small indexed set (5 trials) with no open enrollment listed right now.
Corpus placement: #3,391 of 28,707 conditions by registered trial count.
5 US clinical trials · none currently recruiting · #3,391 of 28,707 conditions by registered trial count
Familial Chylomicronemia Syndrome: 5 US clinical trials tracked, none currently recruiting.
Familial Chylomicronemia Syndrome is the subject of 5 registered US clinical trials on ClinicalTrials.gov, none currently recruiting. 4 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Ionis Pharmaceuticals, running 3 of these trials.
Enrollment posture brief
Registry condition familial-chylomicronemia-syndrome
OPEN 0 | RECR 0% | LATE 4 | EARLY 1 | RANK #3391 | SPON 3
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia (0% recruiting · 12 trials)
Familial Chylomicronemia Syndrome has no open enrollment in this registry pull (5 archived studies). Peers show how other volume-matched labels compare on open share. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Familial Chylomicronemia Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Familial Chylomicronemia Syndrome is recruiting below its size-band peers.
0 of 5 indexed trials (0%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Familial Chylomicronemia Syndrome research.
Ionis Pharmaceuticals accounts for 3 of 5 trials (60%). 3 distinct sponsors appear on at least one study for this condition label.
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Most Familial Chylomicronemia Syndrome trials plan to enrol fewer than 100 people.
Median target enrolment is 67 among the 5 trials that report a genuine target (sentinel values excluded). 4 of those (80%) plan for fewer than 100 participants.
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Familial Chylomicronemia Syndrome research is mostly interventional.
5 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Indexed trials (enrollment closed)
5 total, page 1 of 1
Study of RN0361in Adult Healthy Subjects and Adult Hypertriglyceridemic Subjects
Ikaria Bioscience Pty
NCT06471543
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRx) in Participants With Familial Chylomicronemia Syndrome (FCS)
Ionis Pharmaceuticals
NCT05130450
A Study of Olezarsen (Formerly Known as AKCEA-APOCIII-LRX) Administered to Adults With Familial Chylomicronemia Syndrome (FCS) Previously Treated With Volanesorsen
Ionis Pharmaceuticals
NCT05185843
The Approach Open Label Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Participants With Familial Chylomicronemia Syndrome
Akcea Therapeutics
NCT02658175
The APPROACH Study: A Study of Volanesorsen (Formerly IONIS-APOCIIIRx) in Patients With Familial Chylomicronemia Syndrome
Ionis Pharmaceuticals
NCT02211209
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 3 | 4 |
Top Sponsors
Named interventions
Most-linked intervention names on Familial Chylomicronemia Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Familial Chylomicronemia Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Familial Chylomicronemia Syndrome page
5 registered trials, 0 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- No Familial Chylomicronemia Syndrome trials are currently recruiting in this registry; that can change as new trials post, or check the broader research index. Browse research indexes
- Ionis Pharmaceuticals sponsors the most Familial Chylomicronemia Syndrome trials on record, review their full trial history before evaluating a specific study. See Ionis Pharmaceuticals's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Familial Chylomicronemia Syndrome condition card totals 5 registered trials; most-linked intervention Volanesorsen; top US site state Florida. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.