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NCT04861818 · ClinicalTrials.gov registry record · NA
The Role of the Time of Day in the Effects of Exercise on Memory in Heathy Young Adults
A NA study of Cognitive Change and Aerobic Exercise, sponsored by University of North Carolina, Greensboro.
- Recruiting
- Registry status
- NA
- Development phase
- 80
- Enrollment target
- 1
- Study location
NCT04861818: Recruiting NA study of Cognitive Change and Aerobic Exercise, sponsored by University of North Carolina, Greensboro.
NCT04861818 is a NA study of Cognitive Change and Aerobic Exercise that is actively recruiting participants, run by University of North Carolina, Greensboro. The registered enrollment target is 80 participants, below the 178-participant average among 44 other Cognitive Change trials with a reported enrollment target (55% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04861818, a NA study of Cognitive Change and Aerobic Exercise, is actively recruiting participants, sponsored by University of North Carolina, Greensboro.
- RECRUITING
- Registry status
- NA
- Development phase
- 80 participants
- Enrollment target
- 1
- Study location
Study Summary
Cumulative evidence indicates that a single bout of exercise has beneficial impacts on memory in young adults. From a physiological perspective, acute exercise leads to changes of heart rate variability (HRV), which is associated with memory retrieval process. From a psychological perspective, acute exercise increases the arousal level and thus facilitates cognitive processing including memory storage and retrieval. Such HRV- and/or arousal-based effects of exercise on memory could be differed by the time of day in young adults based on their circadian rhythms of HRV. Moreover, young adults prefer afternoon or evening to morning in their circadian rhythms, demonstrating less wakefulness and lower memory performance in the morning relative to afternoon. Based on the potential psychophysiological mechanisms, exercise could impact young adults' memory differently by the time of day. The investigators aim to 1) determine the extent to which the time of day modulates how moderate-intensity cardiovascular exercise impacts verbal-auditory and visuospatial short- and long-term memory in young adults, and 2) consider potential psychological and physiological markers that may mediate exercise's effects on cognitive performance. As cognitive benefits of exercise might differ by the time of day, it is important to investigate such interaction and make the right recommendations of the timing of exercise for young adults in academic settings.
Primary Outcome
Verbal episodic memory will be assessed immediately and 24 hour after intervention (rest and exercise) using the Auditory Verbal Learning Test (AVLT trial 1 - 8; max/min score: 15/0 for each trial)
Conditions Studied
Interventions
- BEHAVIORAL Moderate-intensity aerobic exercise
Study Locations (1)
North Carolina
- UNC Greensboro - Greensboro
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2021-06-21 |
| Est. Completion | 2025-12-30 |
| Phase | NA |
What NCT04861818 shows while recruiting
NCT04861818 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 178-participant average among 44 other Cognitive Change trials with a reported enrollment target (55% lower).
The record links to 2 conditions, with Cognitive Change appearing as the primary indexed condition, and to 1 intervention - of which Moderate-intensity aerobic exercise is the first listed.
NCT04861818 reports a single indexed study location in North Carolina.
Frequently Asked Questions
What is clinical trial NCT04861818 about?
NCT04861818 is a clinical study titled "The Role of the Time of Day in the Effects of Exercise on Memory in Heathy Young Adults". Cumulative evidence indicates that a single bout of exercise has beneficial impacts on memory in young adults. From a physiological perspective, acute exercise leads to changes of heart rate variability (HRV), which is associated with memory retrieval process. From a psychological perspective, acute...
What is the current status of trial NCT04861818?
This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2021-06-21. Estimated completion is 2025-12-30.
What conditions does trial NCT04861818 study?
This clinical trial studies the following conditions: Cognitive Change, Aerobic Exercise.
What interventions are being tested in trial NCT04861818?
The interventions under investigation include: Moderate-intensity aerobic exercise (BEHAVIORAL).
Who is sponsoring clinical trial NCT04861818?
This trial is sponsored by University of North Carolina, Greensboro, which has 15 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04861818 being conducted?
This trial has 1 study location across North Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT04861818's enrollment target sits among peer trials
80 19th of 44 higher than 23 of 44 other Cognitive Change trials
participants (enrollment target), bucketed by value
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