Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Chronic Migraine, Headache: full-pipeline trial registry
1 of 5 indexed Chronic Migraine, Headache trials are currently recruiting.
Corpus placement: #3,391 of 28,707 conditions by registered trial count.
5 US clinical trials · 1 currently recruiting · #3,391 of 28,707 conditions by registered trial count
Chronic Migraine, Headache: 5 US clinical trials tracked, 1 recruiting.
Chronic Migraine, Headache is the subject of 5 registered US clinical trials on ClinicalTrials.gov, 1 of them currently open to new participants. 1 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Chicago Headache Center & Research Institute, running 1 of these trials.
Enrollment posture brief
Registry condition chronic-migraine-headache
OPEN 1 | RECR 20% | LATE 1 | EARLY 1 | RANK #3391 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Accelerated Phase Chronic Myelogenous Leukemia, BCR-ABL1 Positive (20% recruiting · 10 trials)
Chronic Migraine, Headache lists 1 open slots (20% of 5 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Chronic Migraine, Headache on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Chronic Migraine, Headache is recruiting below its size-band peers.
1 of 5 indexed trials (20%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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One sponsor concentrates Chronic Migraine, Headache research.
Chicago Headache Center & Research Institute accounts for 1 of 5 trials (20%). 5 distinct sponsors appear on at least one study for this condition label.
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Typical Chronic Migraine, Headache enrolment sits around 110 participants.
Median target enrolment is 110 among the 5 trials that report a genuine target (sentinel values excluded). 2 of those (40%) plan for fewer than 100 participants.
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Chronic Migraine, Headache splits between interventional and observational designs.
3 interventional and 2 observational studies make up this index (60% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
5 total, page 1 of 1
Real-world Prospective Study on the Use of Anti-CGRP Drugs in Migraine
Hospital Universitari Vall d'Hebron Research Institute
NCT07159750
Migraine Prevention With the Remote Electrical Neuromodulation (REN) Wearable: A Real-world Evidence Study
Theranica
NCT07487701
COACT Study: CGRPmAbs + OnabotulinumtoxinA Assessment of Chronic Migraine Treatments Study
Chicago Headache Center & Research Institute
NCT05724771
Open Label, 6-month Study for High Frequency and Chronic Migraine,
Ki Health Partners.
NCT06133491
Occipital Nerve Stimulation for the Treatment of Chronic Migraine Headache.
MedtronicNeuro
NCT00200109
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 4 | 1 |
Top Sponsors
Named interventions
Most-linked intervention names on Chronic Migraine, Headache records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Chronic Migraine, Headache trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Chronic Migraine, Headache page
5 registered trials, 1 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 1 Chronic Migraine, Headache trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Chicago Headache Center & Research Institute sponsors the most Chronic Migraine, Headache trials on record, review their full trial history before evaluating a specific study. See Chicago Headache Center & Research Institute's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Chronic Migraine, Headache condition card totals 5 registered trials; most-linked intervention Occipital Nerve Stimulation; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.