Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.

ClinicalTrials.gov 9 recruiting now early-phase tilt

B Acute Lymphoblastic Leukemia: early-phase trial registry

9 of 21 indexed B Acute Lymphoblastic Leukemia trials are currently recruiting, with more weight in Phase 1-2.

Corpus placement: #797 of 28,707 conditions by registered trial count.

21 US clinical trials · 9 currently recruiting · #797 of 28,707 conditions by registered trial count

B Acute Lymphoblastic Leukemia: 21 US clinical trials tracked, 9 recruiting.

B Acute Lymphoblastic Leukemia is the subject of 21 registered US clinical trials on ClinicalTrials.gov, 9 of them currently open to new participants. 6 are in Phase 3-4 (later-stage) and 14 in Phase 1-2 (earlier-stage). The most active sponsor is National Cancer Institute (NCI), running 7 of these trials.

Enrollment posture brief

Registry condition b-acute-lymphoblastic-leukemia

OPEN 9 | RECR 43% | LATE 6 | EARLY 14 | RANK #797 | SPON 7

Nearest open-share peer: Acute Myelogenous Leukemia (AML) (43% recruiting · 7 trials)

B Acute Lymphoblastic Le (th…43%Anal Cancer42.9%Allergic Conjunctivitis14.3%Attention Deficit Disorder W4.8%Adult Acute Myeloid Leukemia0%
Open-enrollment share among volume-matched conditions near B Acute Lymphoblastic Leukemia

B Acute Lymphoblastic Leukemia lists 9 open slots (43% of 21 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →

Key findings

What ClinicalTrials.gov does not surface for B Acute Lymphoblastic Leukemia on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.

  1. B Acute Lymphoblastic Leukemia is recruiting above its size-band peers.

    9 of 21 indexed trials (42.9%) are open to enrollment, against a 39.7% average across 762 conditions with 20-99 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.

  2. One sponsor concentrates B Acute Lymphoblastic Leukemia research.

    National Cancer Institute (NCI) accounts for 7 of 21 trials (33.3%). 9 distinct sponsors appear on at least one study for this condition label.

  3. Most B Acute Lymphoblastic Leukemia trials plan to enrol fewer than 100 people.

    Median target enrolment is 68 among the 21 trials that report a genuine target (sentinel values excluded). 14 of those (66.7%) plan for fewer than 100 participants.

  4. B Acute Lymphoblastic Leukemia research is mostly interventional.

    21 interventional and 0 observational studies make up this index (100% interventional). Study type is sponsor-reported on ClinicalTrials.gov.

Phase 16Phase 28Phase 36

Open and recent trials

21 total, page 1 of 1

RECRUITING Phase 3 5,951 participants

Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy

Children's Oncology Group

NCT03959085

RECRUITING Phase 3 440 participants

Studying the Effect of Levocarnitine in Protecting the Liver From Chemotherapy for Leukemia or Lymphoma

Children's Oncology Group

NCT05602194

RECRUITING Phase 3 222 participants

A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)

National Cancer Institute (NCI)

NCT06124157

RECRUITING Phase 2 153 participants

Testing the Addition of the Anti-cancer Drug Venetoclax and/or the Anti-cancer Immunotherapy Blinatumomab to the Usual Chemotherapy Treatment for Infants With Newly Diagnosed KMT2A-rearranged or KMT2A-non-rearranged Leukemia

National Cancer Institute (NCI)

NCT06317662

RECRUITING Phase 2 80 participants

Blinatumomab, Inotuzumab Ozogamicin, and Combination Chemotherapy as Frontline Therapy in Treating Patients With B Acute Lymphoblastic Leukemia

M.D. Anderson Cancer Center

NCT02877303

RECRUITING NA 50 participants

Evaluating the Effects of Hemoglobin Threshold-specific Packed Red Blood Cell Transfusions on Quality of Life and Functional Outcomes in Patients With High-grade Myeloid Neoplasms, Acute Myeloid Leukemia, or B Acute Lymphoblastic Lymphoma/Leukemia

University of Washington

NCT06710418

RECRUITING Phase 2 30 participants

Local Manufacture of CAR T-Cell Products for the Treatment of B-Cell Lymphoma and B-Acute Lymphoblastic Leukemia

John Lister

NCT05281809

RECRUITING Phase 1 24 participants

Venetoclax and a Pediatric-Inspired Regimen for the Treatment of Newly Diagnosed B Cell Acute Lymphoblastic Leukemia

City of Hope Medical Center

NCT05157971

RECRUITING Phase 1 20 participants

Venetoclax, Dasatinib, Prednisone, Rituximab and Blinatumomab for the Treatment of Newly Diagnosed or Relapsed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia or Mixed Phenotype Acute Leukemia

OHSU Knight Cancer Institute

NCT04872790

ACTIVE NOT RECRUITING Phase 3 6,720 participants

A Study to Investigate Blinatumomab in Combination With Chemotherapy in Patients With Newly Diagnosed B-Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT03914625

ACTIVE NOT RECRUITING Phase 3 5,949 participants

Combination Chemotherapy in Treating Young Patients With Newly Diagnosed High-Risk B Acute Lymphoblastic Leukemia and Ph-Like TKI Sensitive Mutations

National Cancer Institute (NCI)

NCT02883049

ACTIVE NOT RECRUITING Phase 3 475 participants

Imatinib Mesylate and Combination Chemotherapy in Treating Patients With Newly Diagnosed Philadelphia Chromosome Positive Acute Lymphoblastic Leukemia

Children's Oncology Group

NCT03007147

ACTIVE NOT RECRUITING Phase 1 71 participants

Cellular Immunotherapy in Treating Patients With High-Risk Acute Lymphoblastic Leukemia

City of Hope Medical Center

NCT02146924

ACTIVE NOT RECRUITING Phase 2 68 participants

Testing the Combination of Inotuzumab Ozogamicin and Lower Dose Chemotherapy Compared to Usual Chemotherapy for Adults With B-Cell Acute Lymphoblastic Leukemia or B-Cell Lymphoblastic Lymphoma

Alliance for Clinical Trials in Oncology

NCT05303792

ACTIVE NOT RECRUITING Phase 1 56 participants

CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells With or Without NKTR-255 in Adults With Recurrent or Refractory B Cell Malignancies

Stanford University

NCT03233854

ACTIVE NOT RECRUITING Phase 2 53 participants

Blinatumomab and Combination Chemotherapy or Dasatinib, Prednisone, and Blinatumomab in Treating Older Patients With Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT02143414

ACTIVE NOT RECRUITING Phase 2 40 participants

Inotuzumab Ozogamicin in Treating Patients With B-cell Acute Lymphocytic Leukemia With Positive Minimal Residual Disease

M.D. Anderson Cancer Center

NCT03441061

ACTIVE NOT RECRUITING Phase 1 33 participants

Study of CD19/CD22 Chimeric Antigen Receptor (CAR) T Cells in Children and Young Adults w/ Recurrent or Refractory B Cell Malignancies

Stanford University

NCT03241940

ACTIVE NOT RECRUITING Phase 1 18 participants

CD19-Car T Cell Therapy for the Treatment of Older Adults With Acute Lymphoblastic Leukemia in First Remission

City of Hope Medical Center

NCT05707273

COMPLETED Phase 2 78 participants

Azacitidine and Combination Chemotherapy in Treating Infants With Acute Lymphoblastic Leukemia and KMT2A Gene Rearrangement

National Cancer Institute (NCI)

NCT02828358

COMPLETED Phase 2 16 participants

Sapanisertib in Treating Patients With Relapsed and/or Refractory Acute Lymphoblastic Leukemia

National Cancer Institute (NCI)

NCT02484430

Phase Distribution

PhaseTrial count
Phase 1 6
Phase 2 8
Phase 3 6

Named interventions

Most-linked intervention names on B Acute Lymphoblastic Leukemia records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.

Cyclophosphamide Drug
11 trials
Biospecimen Collection Procedure
8 trials
Blinatumomab Biological
6 trials
Cytarabine Drug
6 trials
Calaspargase Pegol Drug
4 trials
Laboratory Biomarker Analysis Other
4 trials
Daunorubicin Hydrochloride Drug
3 trials
Methotrexate Drug
3 trials

US sites by state

Facility locations filed on B Acute Lymphoblastic Leukemia trials. A trial with sites in several states counts in each.

California 16 trials
Arizona 10 trials
Alabama 10 trials
Arkansas 9 trials
Alaska 7 trials
Florida 4 trials
Connecticut 4 trials

Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.

What to do with this B Acute Lymphoblastic Leukemia page

21 registered trials, 9 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.

Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This B Acute Lymphoblastic Leukemia condition card totals 21 registered trials; most-linked intervention Cyclophosphamide; top US site state California. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.