Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Anterior Cruciate Ligament Rupture: later-stage trial registry
4 of 10 indexed Anterior Cruciate Ligament Rupture trials are currently recruiting, with more weight in Phase 3-4.
Corpus placement: #1,724 of 28,707 conditions by registered trial count.
10 US clinical trials · 4 currently recruiting · #1,724 of 28,707 conditions by registered trial count
Anterior Cruciate Ligament Rupture: 10 US clinical trials tracked, 4 recruiting.
Anterior Cruciate Ligament Rupture is the subject of 10 registered US clinical trials on ClinicalTrials.gov, 4 of them currently open to new participants. 2 are in Phase 3-4 (later-stage) and 1 in Phase 1-2 (earlier-stage). The most active sponsor is Andrews Research & Education Foundation, running 1 of these trials.
Enrollment posture brief
Registry condition anterior-cruciate-ligament-rupture
OPEN 4 | RECR 40% | LATE 2 | EARLY 1 | RANK #1724 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Acute Myeloid Leukemia (AML) (40% recruiting · 30 trials)
Anterior Cruciate Ligament Rupture lists 4 open slots (40% of 10 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Anterior Cruciate Ligament Rupture on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Anterior Cruciate Ligament Rupture is recruiting below its size-band peers.
4 of 10 indexed trials (40%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
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Sponsorship of Anterior Cruciate Ligament Rupture trials is spread across many organizations.
Andrews Research & Education Foundation accounts for 1 of 10 trials (10%). 10 distinct sponsors appear on at least one study for this condition label.
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Typical Anterior Cruciate Ligament Rupture enrolment sits around 120 participants.
Median target enrolment is 120 among the 10 trials that report a genuine target (sentinel values excluded). 5 of those (50%) plan for fewer than 100 participants.
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Anterior Cruciate Ligament Rupture research is mostly interventional.
9 interventional and 1 observational studies make up this index (90% interventional). Study type is sponsor-reported on ClinicalTrials.gov.
Open and recent trials
10 total, page 1 of 1
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
Marshall University
NCT06294314
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
Illinois Center for Orthopaedic Research and Education
NCT06979804
BFRT in Adolescents After ACL Reconstruction
Children's Healthcare of Atlanta
NCT04390035
Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction
The Methodist Hospital Research Institute
NCT06511232
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Miach Orthopaedics
NCT03348995
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
University of Colorado, Denver
NCT04039971
Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following ACL Surgery
Sanford Health
NCT06524349
Liposomal Bupivacaine for Pain Control Following Anterior Cruciate Ligament Reconstruction
Emory University
NCT02189317
Acupuncture ACL (Anterior Cruciate Ligament)
Hospital for Special Surgery, New York
NCT03711734
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
Andrews Research & Education Foundation
NCT04088227
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 4 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Anterior Cruciate Ligament Rupture records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Anterior Cruciate Ligament Rupture trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Anterior Cruciate Ligament Rupture page
10 registered trials, 4 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 4 Anterior Cruciate Ligament Rupture trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Andrews Research & Education Foundation sponsors the most Anterior Cruciate Ligament Rupture trials on record, review their full trial history before evaluating a specific study. See Andrews Research & Education Foundation's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Anterior Cruciate Ligament Rupture condition card totals 10 registered trials; most-linked intervention Acupuncture + Standard of Care; top US site state Georgia. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.