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Anterior Cruciate Ligament Rupture clinical trials
Every US clinical trial registered for Anterior Cruciate Ligament Rupture — phase mix, recruiting status, and the sponsors running them, straight from the NIH ClinicalTrials.gov registry.
10 US clinical trials · 4 currently recruiting
The research picture
Anterior Cruciate Ligament Rupture has 10 registered US clinical trials, 4 of them open to new participants right now — about 40% of the total.
- 4
- recruiting participants now
- 40%
- of trials open to enrollment
- 2
- in Phase 3–4 (later-stage)
- 1
- top sponsor: Andrews Research & Education Foundation
Counts reflect the public ClinicalTrials.gov registry as last mirrored by PlainTrial. Status and phase are reported by each study's sponsor. This is reference information, not medical advice.
Active & Recent Trials
Return to Play After ACL Reconstruction With Bone Marrow Aspirate, DBM, and an Internal Brace
Marshall University
NCT06294314
A Comparison of Outcomes After Anterior Cruciate Ligament (ACL) or Anterior Cruciate Ligament and Meniscus (ACL+Meniscus) Surgery Using Semiconductor Fabric Products
Illinois Center for Orthopaedic Research and Education
NCT06979804
BFRT in Adolescents After ACL Reconstruction
Children's Healthcare of Atlanta
NCT04390035
Intraosseous Morphine Administration During Anterior Cruciate Ligament Reconstruction
The Methodist Hospital Research Institute
NCT06511232
The BEAR III Trial for Bridge-Enhanced ACL (Anterior Cruciate Ligament) Restoration
Miach Orthopaedics
NCT03348995
Tendon-Bone Versus All-Soft-Tissue for ACL Reconstruction: A Patient-Blinded Randomized Clinical Trial
University of Colorado, Denver
NCT04039971
Utilization of a 3D Printed Customized Knee Extender and At-Home Rehabilitation Program on Patient Outcomes Following ACL Surgery
Sanford Health
NCT06524349
Liposomal Bupivacaine for Pain Control Following Anterior Cruciate Ligament Reconstruction
Emory University
NCT02189317
Acupuncture ACL (Anterior Cruciate Ligament)
Hospital for Special Surgery, New York
NCT03711734
Effects of Platelet Rich Plasma Injections on Biomarkers After Anterior Cruciate Ligament Tears
Andrews Research & Education Foundation
NCT04088227
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 2 | 1 |
| Phase 4 | 2 |
Top Sponsors
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Reading the Anterior Cruciate Ligament Rupture Trial Landscape
ClinicalTrials.gov lists 10 US studies indexed under Anterior Cruciate Ligament Rupture, and 4 of those are currently open to recruitment — roughly 40% of the total volume on the registry. That ratio is a useful proxy for activity level: a high share of recruiting studies often signals that research interest is current and that new enrollment opportunities are appearing, while a low share typically means the field is dominated by completed or follow-up work where most participant spots have already been filled. These counts reflect the public registry only and include studies at every stage of design, so they should be read as an index of research attention rather than as a measure of treatment availability.
The phase distribution for Anterior Cruciate Ligament Rupture shows 2 late-stage studies (Phase 3 and Phase 4 combined) alongside 1 earlier-phase entries (Phase 1 through Phase 2). Phase 1 and Phase 2 studies focus on early safety signals, dosing, and preliminary effect, while Phase 3 studies are typically the larger efficacy and safety trials submitted toward regulatory review, and Phase 4 studies follow approved interventions in real-world use. A condition weighted toward later phases often reflects a mature research pipeline with several interventions already close to or past approval, whereas a heavier early-phase tilt suggests the field is still exploring new mechanisms and candidate approaches.
Top sponsor activity for Anterior Cruciate Ligament Rupture is led by Andrews Research & Education Foundation with 1 indexed trial, alongside 9 other organizations in the top contributor list. The list on this page surfaces up to 10 of the most relevant recent and active entries, ordered with recruiting studies first so practical options are visible. All figures are derived from the public ClinicalTrials.gov dataset maintained by the National Library of Medicine and are reproduced here for reference. Inclusion of a trial, sponsor, or intervention on this page is neither an endorsement nor a recommendation — eligibility, protocol changes, and site-level status can shift frequently, so always verify current details on ClinicalTrials.gov and consult a qualified healthcare provider before acting on anything you see here.
Frequently Asked Questions
How many clinical trials are there for Anterior Cruciate Ligament Rupture?
PlainTrial tracks 10 US clinical trials for Anterior Cruciate Ligament Rupture, of which 4 are currently recruiting participants. Data sourced from ClinicalTrials.gov.
How do I find a recruiting trial for Anterior Cruciate Ligament Rupture?
Use the trial list above filtered by "Recruiting" status, or visit our trial finder at /recruiting to search by condition and state. Always discuss trial participation with your healthcare provider before enrolling.
Is this data current?
Data is sourced from ClinicalTrials.gov and reflects our most recent data pull. Trial status may have changed since then. Always verify current information at ClinicalTrials.gov before making decisions about participation.
Related
Disclaimer: This information is provided for informational purposes only and does not constitute professional advice. Data is sourced from ClinicalTrials.gov (National Library of Medicine). Consult a qualified professional before making decisions based on this data.
Read our methodology — how this data is sourced, computed, and verified.
Source: ClinicalTrials.gov (NIH/NLM) ClinicalTrials.gov AACT registry · 2026 Trial counts and statuses sourced from ClinicalTrials.gov. Sponsor counts include both industry and federal/academic sponsors.