Medical Information Only. Consult your healthcare provider before considering clinical trial enrollment.
Acute Chest Syndrome: early-phase trial registry
2 of 4 indexed Acute Chest Syndrome trials are currently recruiting, with more weight in Phase 1-2.
Corpus placement: #4,115 of 28,707 conditions by registered trial count.
4 US clinical trials · 2 currently recruiting · #4,115 of 28,707 conditions by registered trial count
Acute Chest Syndrome: 4 US clinical trials tracked, 2 recruiting.
Acute Chest Syndrome is the subject of 4 registered US clinical trials on ClinicalTrials.gov, 2 of them currently open to new participants. 0 are in Phase 3-4 (later-stage) and 3 in Phase 1-2 (earlier-stage). The most active sponsor is Gary M Brittenham, MD, running 1 of these trials.
Enrollment posture brief
Registry condition acute-chest-syndrome
OPEN 2 | RECR 50% | LATE 0 | EARLY 3 | RANK #4115 | SPON 1
Volume-matched condition peers
Nearest open-share peer: Abdominal Aortic Aneurysms (50% recruiting · 6 trials)
Acute Chest Syndrome lists 2 open slots (50% of 4 indexed trials). Peers are matched on registered volume, not therapeutic-area browse lists. How peer matching works →
Key findings
What ClinicalTrials.gov does not surface for Acute Chest Syndrome on its own pages , computed from the registry mirror as of 2026-08-08. Each line carries its own denominator so it can be quoted as it stands.
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Acute Chest Syndrome is recruiting above its size-band peers.
2 of 4 indexed trials (50%) are open to enrollment, against a 46.5% average across 27,806 conditions with fewer than 20 trials. The peer set uses the same ClinicalTrials.gov-derived counts as this page.
Open and recent trials
4 total, page 1 of 1
Tocilizumab for Acute Chest Syndrome
University of Chicago
NCT05640271
Ultrasound Acute Chest Syndrome Sickle Cell Disease
Indiana University
NCT06880679
Vitamin D for Sickle-cell Respiratory Complications
Gary M Brittenham, MD
NCT01443728
Inhaled Corticosteroid Use to Prevent Acute Chest Syndrome Recurrence in Children Between 1 and 4 With Sickle Cell Disease: a Feasibility Trial
Vanderbilt University
NCT02187445
Phase Distribution
| Phase | Trial count |
|---|---|
| Phase 1 | 1 |
| Phase 2 | 2 |
Top Sponsors
Named interventions
Most-linked intervention names on Acute Chest Syndrome records (sponsor-reported on ClinicalTrials.gov). Counts are trial links, not unique products.
US sites by state
Facility locations filed on Acute Chest Syndrome trials. A trial with sites in several states counts in each.
Source: ClinicalTrials.gov, National Library of Medicine. Data is informational only.
Related
What to do with this Acute Chest Syndrome page
4 registered trials, 2 currently recruiting, is a starting point for a conversation, not a diagnosis or a recommendation.
- 2 Acute Chest Syndrome trials are currently recruiting, check eligibility criteria before contacting a site. Browse recruiting trials
- Gary M Brittenham, MD sponsors the most Acute Chest Syndrome trials on record, review their full trial history before evaluating a specific study. See Gary M Brittenham, MD's trials
- Bring the specific trial ID (NCT number) to your own doctor before enrolling, this page is a directory, not medical guidance. Read the trial-finding guide
Trial and recruiting counts reflect ClinicalTrials.gov registry status as of the data vintage above; individual trial eligibility and enrollment status can change.
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This Acute Chest Syndrome condition card totals 4 registered trials; most-linked intervention Active Comparator: Vitamin D3 12,000 IU; top US site state Tennessee. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.