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NCT07687745 · ClinicalTrials.gov registry record · Early Phase 1
Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy
A Early Phase 1 study, sponsored by University of Arizona.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 80
- Enrollment target
NCT07687745: Recruiting Early Phase 1 study, sponsored by University of Arizona.
NCT07687745 is a Early Phase 1 study that is actively recruiting participants, run by University of Arizona. The registered enrollment target is 80 participants, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% higher). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07687745, a Early Phase 1 study, is actively recruiting participants, sponsored by University of Arizona.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 80 participants
- Enrollment target
Study Summary
This is an interventional study that will test whether a breathing exercise called Inspiratory Muscle Strength Training (IMST) can safely and effectively lower blood pressure during late pregnancy. The goal is to see if a home-based breathing training can help prevent or reduce high blood pressure disorders in pregnancy. The main objectives are to make sure the training is safe and tolerable for pregnant women and to examine blood pressure and blood vessel health. Participants in their third trimester will be randomly assigned to either do moderate resistance IMST or a minimal resistance sham IMST, for 5 to 8 minutes a day over six weeks.
Primary Outcome
Percentage of training sessions associated with abnormal post-training fetal heart rate (FHR) tracing, or with maternal oxygen desaturation (SpO2) or symptoms (e.g., perceived exertion, lightheadedness, hyperventilation), as assessed by study staff during non-stress test (NST) and clinic visits.
Interventions
- OTHER Exercise at 15% PI max
- OTHER Exercise at 50% PI max
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2026-06-08 |
| Est. Completion | 2027-09-30 |
| Phase | Early Phase 1 |
What NCT07687745 shows while recruiting
NCT07687745 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, above the 53-participant average among 2,764 other Early Phase 1 trials with a reported enrollment target (51% higher).
The record links to 0 conditions, and to 2 interventions - of which Exercise at 15% PI max is the first listed.
NCT07687745 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07687745 about?
NCT07687745 is a clinical study titled "Breathing for Two: Inspiratory Muscle Strength Training for Supporting Healthy Blood Pressure in Pregnancy". This is an interventional study that will test whether a breathing exercise called Inspiratory Muscle Strength Training (IMST) can safely and effectively lower blood pressure during late pregnancy. The goal is to see if a home-based breathing training can help prevent or reduce high blood pressure d...
What is the current status of trial NCT07687745?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 80 participants. The study started on 2026-06-08. Estimated completion is 2027-09-30.
What interventions are being tested in trial NCT07687745?
The interventions under investigation include: Exercise at 15% PI max (OTHER), Exercise at 50% PI max (OTHER).
Who is sponsoring clinical trial NCT07687745?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07687745's enrollment target sits among peer trials
80 271st of 2000 higher than 1,704 of 2,000 other Early Phase 1 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Early Phase 1 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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