Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07662109 · ClinicalTrials.gov registry record · Phase 3

A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus

A Phase 3 study, sponsored by AstraZeneca.

Not yet
Registry status
Phase 3
Development phase
2,000
Enrollment target

NCT07662109: Clinical Trial Phase 3 study, sponsored by AstraZeneca.

NCT07662109 is a Phase 3 study that has not yet begun recruiting, run by AstraZeneca. The registered enrollment target is 2,000 participants, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (159% higher). According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07662109, a Phase 3 study, has not yet begun recruiting, sponsored by AstraZeneca.

NOT YET RECRUITING
Registry status
Phase 3
Development phase
2,000 participants
Enrollment target

Study Summary

The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron and dapagliflozin in combination, compared with elecoglipron alone and dapagliflozin alone, in adults with type 2 diabetes mellitus (T2DM) inadequately managed with lifestyle management alone or treated with other background glucose-lowering medication.

Interventions

  • DRUG Dapagliflozin
  • DRUG Elecoglipron
  • DRUG Elecoglipron-matched placebo
  • DRUG Dapagliflozin-matched placebo

Trial Details

FieldValue
Enrollment Target 2,000 participants
Start Date 2026-07-06
Est. Completion 2028-07-05
Phase Phase 3
AstraZeneca

1,285 total trials

What is known before NCT07662109 opens enrollment

NCT07662109 is an interventional study that assigns participants to a tested intervention. Its 2,000 participants enrollment target places it among the larger protocols in the corpus, above the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (159% higher).

The record links to 0 conditions, and to 4 interventions - of which Dapagliflozin is the first listed.

NCT07662109 does not publish any study locations in the registry export this page uses.

Frequently Asked Questions

What is clinical trial NCT07662109 about?

NCT07662109 is a clinical study titled "A Phase III Study to Investigate the Efficacy and Safety of the Combination of Elecoglipron and Dapagliflozin in Adults With Type 2 Diabetes Mellitus". The purpose of this study is to evaluate the efficacy, safety, and tolerability of elecoglipron and dapagliflozin in combination, compared with elecoglipron alone and dapagliflozin alone, in adults with type 2 diabetes mellitus (T2DM) inadequately managed with lifestyle management alone or treated w...

What is the current status of trial NCT07662109?

This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 2,000 participants. The study started on 2026-07-06. Estimated completion is 2028-07-05.

What interventions are being tested in trial NCT07662109?

The interventions under investigation include: Dapagliflozin (DRUG), Elecoglipron (DRUG), Elecoglipron-matched placebo (DRUG), Dapagliflozin-matched placebo (DRUG).

Who is sponsoring clinical trial NCT07662109?

This trial is sponsored by AstraZeneca, which has 1,285 total clinical trials registered on ClinicalTrials.gov.

How this trial's enrollment target compares

Where NCT07662109's enrollment target sits among peer trials

2,000 100th of 2000 higher than 1,895 of 2,000 other Phase 3 trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT00001465 · 2,000 participants

    Study of the Disease Process of Lymphangioleiomyomatosis

  • NCT00001595 · 2,000 participants

    An Investigation of Pituitary Tumors and Related Hypothalmic Disorders

  • NCT00138931 · 2,000 participants

    Genetics of Cardiovascular and Neuromuscular Disease

  • NCT00288119 · 2,000 participants

    Genetic Determinants of Barrett's Esophagus and Esophageal Adenocarcinoma

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07662109, the US trial registry maintained by the National Library of Medicine. NCT07662109 (large enrollment · none site footprint · not yet recruiting) retrieved and formatted by PlainTrial, see methodology.