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NCT07525219 · ClinicalTrials.gov registry record · Phase 3
Suzetrigine Frame Trial Comparing Suzetrigine and Acetaminophen
A Phase 3 study, sponsored by Wake Forest University Health Sciences.
- Not yet
- Registry status
- Phase 3
- Development phase
- 80
- Enrollment target
NCT07525219: Clinical Trial Phase 3 study, sponsored by Wake Forest University Health Sciences.
NCT07525219 is a Phase 3 study that has not yet begun recruiting, run by Wake Forest University Health Sciences. The registered enrollment target is 80 participants, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (90% lower). According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07525219, a Phase 3 study, has not yet begun recruiting, sponsored by Wake Forest University Health Sciences.
- NOT YET RECRUITING
- Registry status
- Phase 3
- Development phase
- 80 participants
- Enrollment target
Study Summary
Local anesthetic infiltration is a primary source of acute pain during stereotactic procedures.
Primary Outcome
A single consolidated VAS score (0-10) representing the pain experienced during the administration of local anesthetic across all four pin sites. This VAS is administered immediately after the local anesthetic injections are completed. For anxiety-VAS cutoff value = 40: the VAS score is ≥40 in 81% of patients with anxiety (sensitivity); the VAS score is \<40 in 70% of patients without anxiety (specificity); 67% of patients with a VAS score ≥ 40 have anxiety (PPV); 82% of patients with a VAS sco
Interventions
- DRUG Suzetrigine
- DRUG acetaminophen
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 80 participants |
| Start Date | 2026-07 |
| Est. Completion | 2027-07 |
| Phase | Phase 3 |
What is known before NCT07525219 opens enrollment
NCT07525219 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 772-participant average among 15,282 other Phase 3 trials with a reported enrollment target (90% lower).
The record links to 0 conditions, and to 2 interventions - of which Suzetrigine is the first listed.
NCT07525219 does not publish any study locations in the registry export this page uses.
Frequently Asked Questions
What is clinical trial NCT07525219 about?
NCT07525219 is a clinical study titled "Suzetrigine Frame Trial Comparing Suzetrigine and Acetaminophen". Local anesthetic infiltration is a primary source of acute pain during stereotactic procedures.
What is the current status of trial NCT07525219?
This trial is currently not yet recruiting. It is a Phase 3 study. The enrollment target is 80 participants. The study started on 2026-07. Estimated completion is 2027-07.
What interventions are being tested in trial NCT07525219?
The interventions under investigation include: Suzetrigine (DRUG), acetaminophen (DRUG).
Who is sponsoring clinical trial NCT07525219?
This trial is sponsored by Wake Forest University Health Sciences, which has 1,140 total clinical trials registered on ClinicalTrials.gov.
Learn More About Clinical Trials
How this trial's enrollment target compares
Where NCT07525219's enrollment target sits among peer trials
80 1755th of 2000 higher than 233 of 2,000 other Phase 3 trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Phase 3 trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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