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A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324
NCT07484074 · View on ClinicalTrials.gov ↗
Study Summary
A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324
Conditions Studied
Interventions
- DRUG Faricimab
- DRUG OLN324
Study Locations (20)
California
- Glendale, CA — Glendale
- Pasadena, CA — Pasadena
- Sacramento, CA — Sacramento
- Walnut Creek, CA — Walnut Creek
Florida
- Fort Myers, FL — Fort Myers
- Saint Petersburg, FL — St. Petersburg
- Winter Haven, FL — Winter Haven
Texas
- Abilene, TX — Abilene
- Arlington, TX — Arlington
- Austin, TX — Austin
Arizona
- Phoenix, AZ — Phoenix
Connecticut
- Waterford, CT — Waterford
Illinois
- Oak Forest, IL — Oak Forest
Maryland
- Hagerstown, MD — Hagerstown
Michigan
- Grand Rapids, MI — Grand Rapids
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 164 participants |
| Start Date | 2025-02-12 |
| Est. Completion | 2025-12-09 |
| Phase | Phase 1 |
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Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07484074
The ClinicalTrials.gov registry entry for NCT07484074 describes a study currently listed as completed. It is categorized as Phase 1, which is the standard way researchers label where a study sits along the investigational pathway from early safety work through later efficacy and post-marketing evaluation. The registered enrollment target is 164 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Ollin Biosciences, which has 1 total studies on file at ClinicalTrials.gov, and sponsors are the parties responsible for study design, oversight, and regulatory filings.
The record links to 2 conditions, with Diabetic Macular Edema (DME) appearing as the primary indexed condition, and to 2 interventions — of which Faricimab is the first listed. Interventions can include drugs, devices, procedures, behavioral programs, or observational arms, and each is tracked as a separate registry field so that downstream queries can filter accurately. When a trial lists multiple interventions, it usually reflects a multi-arm design or a comparison protocol rather than a single treatment being tested in isolation. The brief summary published in the registry is the clearest source of protocol intent and should be read before drawing conclusions from any sidebar tags.
Geographic footprint matters for practical reasons: NCT07484074 reports 20 study locations spanning 13 distinct geographic areas — top geographies include California, Florida, Texas. A larger site network tends to correlate with broader recruitment capacity, but it does not imply anything about study quality, and site-level enrollment status can diverge from the overall registry status shown above. Every data point on this page comes from the public ClinicalTrials.gov dataset and is reproduced here for reference only; it is not a medical recommendation, an endorsement of the sponsor, or an invitation to enroll. Verify current status, eligibility criteria, and contact details directly at ClinicalTrials.gov, and discuss any participation decision with your own healthcare provider.
Frequently Asked Questions
What is clinical trial NCT07484074 about?
NCT07484074 is a clinical study titled "A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324". A Phase 1b Study to Assess the Safety, Tolerability, Pharmacokinetics, and Exploratory Efficacy of Intravitreal OLN324
What is the current status of trial NCT07484074?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 164 participants. The study started on 2025-02-12. Estimated completion is 2025-12-09.
What conditions does trial NCT07484074 study?
This clinical trial studies the following conditions: Diabetic Macular Edema (DME), Neovascular (Wet) Age-Related Macular Degeneration. These conditions were identified from the trial registry and reflect the primary focus areas of the research.
What interventions are being tested in trial NCT07484074?
The interventions under investigation include: Faricimab (DRUG), OLN324 (DRUG). Each intervention is being evaluated for safety and efficacy as part of this clinical study.
Who is sponsoring clinical trial NCT07484074?
This trial is sponsored by Ollin Biosciences, which has 1 total clinical trials registered on ClinicalTrials.gov. The sponsor is responsible for the study's design, funding, and regulatory compliance.
Where is trial NCT07484074 being conducted?
This trial has 20 study locations across Arizona, California, Connecticut, Florida, Illinois. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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