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NCT07473102 · ClinicalTrials.gov registry record · Early Phase 1

PET Imaging of MMP Activation in AAA: Clinical Component

A Early Phase 1 study of Abdominal Aortic Aneurysm, sponsored by Washington University School of Medicine.

Recruiting
Registry status
Early Phase 1
Development phase
28
Enrollment target
1
Study location

NCT07473102 is a Early Phase 1 study of Abdominal Aortic Aneurysm that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 28 participants, below the 452-participant average among 16 other Abdominal Aortic Aneurysm trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07473102, a Early Phase 1 study of Abdominal Aortic Aneurysm, is actively recruiting participants, sponsored by Washington University School of Medicine.

RECRUITING
Registry status
Early Phase 1
Development phase
28 participants
Enrollment target
1
Study location

Study Summary

A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale), evaluate radiotracer pharmacodynamics and correlate PET imaging characteristics (WU) with ex vivo tissue measurements (Yale).

Conditions Studied

Interventions

  • DRUG Cu-64-RYM2
  • DRUG PET imaging using Cu-64

Study Locations (1)

Missouri

  • Washington University School of Medicine - St Louis

Trial Details

FieldValue
Enrollment Target 28 participants
Start Date 2025-11-03
Est. Completion 2027-03-31
Phase Early Phase 1

What the Registry Record Tells You About NCT07473102

The ClinicalTrials.gov registry entry for NCT07473102 describes a study currently listed as recruiting, categorized as Early Phase 1. The registered enrollment target is 28 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 452-participant average among 16 other Abdominal Aortic Aneurysm trials with a reported enrollment target (94% lower). The listed sponsor is Washington University School of Medicine, which has 1,502 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Abdominal Aortic Aneurysm appearing as the primary indexed condition, and to 2 interventions - of which Cu-64-RYM2 is the first listed.

NCT07473102 reports 1 study location spanning 1 distinct geographic area - top geographies include Missouri.

Frequently Asked Questions

What is clinical trial NCT07473102 about?

NCT07473102 is a clinical study titled "PET Imaging of MMP Activation in AAA: Clinical Component". A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale), evaluate radiotracer pharmacodynamics and correlate PET imaging characteri...

What is the current status of trial NCT07473102?

This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 28 participants. The study started on 2025-11-03. Estimated completion is 2027-03-31.

What conditions does trial NCT07473102 study?

This clinical trial studies the following conditions: Abdominal Aortic Aneurysm.

What interventions are being tested in trial NCT07473102?

The interventions under investigation include: Cu-64-RYM2 (DRUG), PET imaging using Cu-64 (DRUG).

Who is sponsoring clinical trial NCT07473102?

This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07473102 being conducted?

This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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