Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT07473102 · ClinicalTrials.gov registry record · Early Phase 1
PET Imaging of MMP Activation in AAA: Clinical Component
A Early Phase 1 study of Abdominal Aortic Aneurysm, sponsored by Washington University School of Medicine.
- Recruiting
- Registry status
- Early Phase 1
- Development phase
- 28
- Enrollment target
- 1
- Study location
NCT07473102: Recruiting Early Phase 1 study of Abdominal Aortic Aneurysm, sponsored by Washington University School of Medicine.
NCT07473102 is a Early Phase 1 study of Abdominal Aortic Aneurysm that is actively recruiting participants, run by Washington University School of Medicine. The registered enrollment target is 28 participants, below the 452-participant average among 16 other Abdominal Aortic Aneurysm trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07473102, a Early Phase 1 study of Abdominal Aortic Aneurysm, is actively recruiting participants, sponsored by Washington University School of Medicine.
- RECRUITING
- Registry status
- Early Phase 1
- Development phase
- 28 participants
- Enrollment target
- 1
- Study location
Study Summary
A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale), evaluate radiotracer pharmacodynamics and correlate PET imaging characteristics (WU) with ex vivo tissue measurements (Yale).
Primary Outcome
Verification Cu-64RYM-2 signal is present in AAA segment of the abdominal aorta
Conditions Studied
Interventions
- DRUG Cu-64-RYM2
- DRUG PET imaging using Cu-64
Study Locations (1)
Missouri
- Washington University School of Medicine - St Louis
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 28 participants |
| Start Date | 2025-11-03 |
| Est. Completion | 2027-03-31 |
| Phase | Early Phase 1 |
What NCT07473102 shows while recruiting
NCT07473102 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 28 participants, a relatively small participant target, below the 452-participant average among 16 other Abdominal Aortic Aneurysm trials with a reported enrollment target (94% lower).
The record links to 1 condition, with Abdominal Aortic Aneurysm appearing as the primary indexed condition, and to 2 interventions - of which Cu-64-RYM2 is the first listed.
NCT07473102 reports a single indexed study location in Missouri.
Frequently Asked Questions
What is clinical trial NCT07473102 about?
NCT07473102 is a clinical study titled "PET Imaging of MMP Activation in AAA: Clinical Component". A first-in-human evaluation of \[64Cu\]-RYM2 with PET/CT will be performed to: a) assess its safety, biodistribution, and radiation dosimetry in normal volunteers (WU) and; b) in AAA patients undergoing surgery (WU and Yale), evaluate radiotracer pharmacodynamics and correlate PET imaging characteri...
What is the current status of trial NCT07473102?
This trial is currently recruiting. It is a Early Phase 1 study. The enrollment target is 28 participants. The study started on 2025-11-03. Estimated completion is 2027-03-31.
What conditions does trial NCT07473102 study?
This clinical trial studies the following conditions: Abdominal Aortic Aneurysm.
What interventions are being tested in trial NCT07473102?
The interventions under investigation include: Cu-64-RYM2 (DRUG), PET imaging using Cu-64 (DRUG).
Who is sponsoring clinical trial NCT07473102?
This trial is sponsored by Washington University School of Medicine, which has 1,502 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07473102 being conducted?
This trial has 1 study location across Missouri. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Abdominal Aortic Aneurysm
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07473102's enrollment target sits among peer trials
28 15th of 16 higher than 2 of 16 other Abdominal Aortic Aneurysm trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Abdominal Aortic Aneurysm trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Terumo Aortic Global Endovascular Registry
RECRUITING
-
Limiting AAA With Metformin (LIMIT) Trial
RECRUITING · Phase 2
-
Endurant Stent Graft System vs Excluder Endoprothesis: ADVANCE Trial
RECRUITING · NA
-
Nectero EAST System Clinical Study
RECRUITING · Phase 2
-
The Long-Term EVAR Assessment and Follow-Up (LEAF) Study for the AFX2 System
RECRUITING
-
Magnetic Resonance Elastography in Patients With Abdominal Aortic Aneurysms
RECRUITING
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT03471117 · 28 participants · Phase 4
Pioglitazone to Reduce Sympathetic Overactivity in CKD Patients
- NCT03523975 · 28 participants · Phase 1
Venetoclax, Lenalidomide and Rituximab in Patients With Previously Untreated Mantle Cell Lymphoma
- NCT03608631 · 28 participants · Phase 1
iExosomes in Treating Participants With Metastatic Pancreas Cancer With KrasG12D Mutation
- NCT03810651 · 28 participants · Early Phase 1
Pencil Beam Scanning in Patients With Renal Tumors
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI