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NCT07431398 · ClinicalTrials.gov registry record · Phase 1
Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell Disease
A Phase 1 study of Sickle Cell Disease, sponsored by Fulcrum Therapeutics.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 24
- Enrollment target
- 6
- Study locations
NCT07431398 is a Phase 1 study of Sickle Cell Disease that is actively recruiting participants, run by Fulcrum Therapeutics. The registered enrollment target is 24 participants, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (92% lower). The trial reports 6 study locations across 4 states.
The verdict
NCT07431398, a Phase 1 study of Sickle Cell Disease, is actively recruiting participants, sponsored by Fulcrum Therapeutics.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 24 participants
- Enrollment target
- 6
- Study locations
Study Summary
This clinical trial is a study to evaluate the pharmacokinetics of the tablet formulation Pociredir in fasted and fed state participants with Sickle Cell Disease (SCD).
Conditions Studied
Interventions
- DRUG Pociredir
Study Locations (6)
Florida
- Advanced Pharma - Miami - Miami
- Omega Research Group - Orlando
Texas
- University of Texas Health Science Center Houston - Houston
- Worldwide Clinical Trials - San Antonio
Georgia
- Sonar Clinical Research - Riverdale
Ohio
- Neuro-Behavioral Clinical Research - North Canton
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 24 participants |
| Start Date | 2025-12-13 |
| Est. Completion | 2026-04 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07431398
The ClinicalTrials.gov registry entry for NCT07431398 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 24 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 293-participant average among 213 other Sickle Cell Disease trials with a reported enrollment target (92% lower). The listed sponsor is Fulcrum Therapeutics, which has 8 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Sickle Cell Disease appearing as the primary indexed condition, and to 1 intervention - of which Pociredir is the first listed.
NCT07431398 reports 6 study locations spanning 4 distinct geographic areas - top geographies include Florida, Texas, Georgia.
Frequently Asked Questions
What is clinical trial NCT07431398 about?
NCT07431398 is a clinical study titled "Single-dose Pharmacokinetics of Pociredir in Participants With Sickle Cell Disease". This clinical trial is a study to evaluate the pharmacokinetics of the tablet formulation Pociredir in fasted and fed state participants with Sickle Cell Disease (SCD).
What is the current status of trial NCT07431398?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 24 participants. The study started on 2025-12-13. Estimated completion is 2026-04.
What conditions does trial NCT07431398 study?
This clinical trial studies the following conditions: Sickle Cell Disease.
What interventions are being tested in trial NCT07431398?
The interventions under investigation include: Pociredir (DRUG).
Who is sponsoring clinical trial NCT07431398?
This trial is sponsored by Fulcrum Therapeutics, which has 8 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07431398 being conducted?
This trial has 6 study locations across Florida, Georgia, Ohio, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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Read our methodology - how this data is sourced, computed, and verified.
Related
Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.