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NCT05174936 · ClinicalTrials.gov registry record · NA
ResIlience-based Stigma REdUction Program ("Rise-up")
A NA study of HIV/AIDS and Stigma, Social, sponsored by University of South Carolina.
- Active
- Registry status
- NA
- Development phase
- 1,928
- Enrollment target
- 1
- Study location
NCT05174936: Active NA study of HIV/AIDS and Stigma, Social, sponsored by University of South Carolina.
NCT05174936 is a NA study of HIV/AIDS and Stigma, Social that is active but no longer recruiting, run by University of South Carolina. The registered enrollment target is 1,928 participants, below the 33,149-participant average among 61 other HIV/AIDS trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT05174936, a NA study of HIV/AIDS and Stigma, Social, is active but no longer recruiting, sponsored by University of South Carolina.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 1,928 participants
- Enrollment target
- 1
- Study location
Study Summary
Stigma and discrimination related to HIV and AIDS ("HIV-related stigma") have been identified worldwide as major barriers to HIV treatment and care, posing challenges to HIV prevention efforts and provision of adequate care, support, and treatment. Despite decades of global efforts to tackle HIV-related stigma, previous interventions designed to reduce stigma have been largely ineffective. The knowledge gaps and challenges for combating HIV-related stigma are partly rooted in the complexity and diversity of the stigma and partly in the limitations in current conceptualization of stigma reduction efforts. Recent research, including our own preliminary data, has shown the promise of resilience approaches that focus on the development of strengths, competencies, resources, and capacities of people living with HIV (PLWH) and those of their real or surrogate family members and healthcare facilities to prevent, reduce, and mitigate the negative effects of stigma. However, the resilience approach, while hypothesized, has not been widely tested in intervention trials. In the current application, we propose to develop, implement, and evaluate a theory-guided, multilevel multimode resilience-based intervention via a stepped-wedge randomized trial among 800 PLWH and their real or surrogate family members as well as 320 healthcare providers in Guangxi, China where we have built a strong research infrastructure and community collaboration through NIH-funded research since 2004. The primary outcome will be viral suppression among PLWH, and the intermediate outcomes will include resilience resources at the levels of individuals, the real or surrogate family members, and healthcare facilities as well as chronic stress response and adherence to treatment and care. The proposed study is innovative as it addresses a number of knowledge gaps in HIV-related stigma reduction intervention research based on both a conceptualization of stigma reduction and advancement in intervention resear
Primary Outcome
The most recent viral load
Conditions Studied
Interventions
- BEHAVIORAL PLWH intervention
- BEHAVIORAL Family member intervention
- BEHAVIORAL Healthcare provider intervention
Study Locations (1)
South Carolina
- University of South Carolina - Columbia
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 1,928 participants |
| Start Date | 2023-11-01 |
| Est. Completion | 2027-11-30 |
| Phase | NA |
What the registry record for NCT05174936 still lists
NCT05174936 is an interventional study that assigns participants to a tested intervention. Its 1,928 participants enrollment target places it among the larger protocols in the corpus, below the 33,149-participant average among 61 other HIV/AIDS trials with a reported enrollment target (94% lower).
The record links to 3 conditions, with HIV/AIDS appearing as the primary indexed condition, and to 3 interventions - of which PLWH intervention is the first listed.
NCT05174936 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT05174936 about?
NCT05174936 is a clinical study titled "ResIlience-based Stigma REdUction Program ("Rise-up")". Stigma and discrimination related to HIV and AIDS ("HIV-related stigma") have been identified worldwide as major barriers to HIV treatment and care, posing challenges to HIV prevention efforts and provision of adequate care, support, and treatment. Despite decades of global efforts to tackle HIV-rel...
What is the current status of trial NCT05174936?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 1,928 participants. The study started on 2023-11-01. Estimated completion is 2027-11-30.
What conditions does trial NCT05174936 study?
This clinical trial studies the following conditions: HIV/AIDS, Stigma, Social, Emotional Adjustment.
What interventions are being tested in trial NCT05174936?
The interventions under investigation include: PLWH intervention (BEHAVIORAL), Family member intervention (BEHAVIORAL), Healthcare provider intervention (BEHAVIORAL).
Who is sponsoring clinical trial NCT05174936?
This trial is sponsored by University of South Carolina, which has 157 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT05174936 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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1,928 4th of 61 higher than 58 of 61 other HIV/AIDS trials
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