Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07217054 · ClinicalTrials.gov registry record

Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder

A clinical trial of Parkinson Disease and Parkinson's Disease, sponsored by CND Life Sciences.

Recruiting
Registry status
40
Enrollment target
1
Study location

NCT07217054: Recruiting study of Parkinson Disease and Parkinson's Disease, sponsored by CND Life Sciences.

NCT07217054 is a study of Parkinson Disease and Parkinson's Disease that is actively recruiting participants, run by CND Life Sciences. The registered enrollment target is 40 participants, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07217054, a study of Parkinson Disease and Parkinson's Disease, is actively recruiting participants, sponsored by CND Life Sciences.

RECRUITING
Registry status
40 participants
Enrollment target
1
Study location

Study Summary

The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease or REM Sleep Behavior Disorder (RBD). The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon tissue samples from people with Parkinson's disease and RBD? Currently, Parkinson's disease is diagnosed by observing symptoms like tremors and movement problems and RBD by loss of muscle atonia during REM sleep, but by then the disease has already progressed significantly. Earlier detection could help doctors start treatment sooner.

Study Locations (1)

Connecticut

  • Digestive Disease Associates - Branford

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-11-04
Est. Completion 2029-10
CND Life Sciences

8 total trials

What NCT07217054 shows while recruiting

NCT07217054 is an observational study that tracks outcomes without assigning an intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 5,326-participant average among 297 other Parkinson Disease trials with a reported enrollment target (99% lower).

The record links to 4 conditions, with Parkinson Disease appearing as the primary indexed condition, and to 0 interventions.

NCT07217054 reports a single indexed study location in Connecticut.

Frequently Asked Questions

What is clinical trial NCT07217054 about?

NCT07217054 is a clinical study titled "Colonic Tissue Biopsy Detection of Phosphorylated Alpha-synuclein for Parkinson's Diagnosis or REM Sleep Behavior Disorder". The goal of this observational study is to learn whether tissue samples taken from the colon during routine colonoscopy can detect signs of Parkinson's disease or REM Sleep Behavior Disorder (RBD). The main question it aims to answer is: Can doctors find a protein called alpha-synuclein in colon ti...

What is the current status of trial NCT07217054?

This trial is currently recruiting. The enrollment target is 40 participants. The study started on 2025-11-04. Estimated completion is 2029-10.

What conditions does trial NCT07217054 study?

This clinical trial studies the following conditions: Parkinson Disease, Parkinson's Disease, PARKINSON DISEASE (Disorder), Parkinson.

Who is sponsoring clinical trial NCT07217054?

This trial is sponsored by CND Life Sciences, which has 8 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07217054 being conducted?

This trial has 1 study location across Connecticut. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Parkinson Disease

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07217054's enrollment target sits among peer trials

40 173rd of 297 higher than 109 of 297 other Parkinson Disease trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Parkinson Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

Nationwide trials with similar profiles

Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.

Similar enrollment target

  • NCT01306019 · 40 participants · Phase 1

    Lentiviral Gene Transfer for Treatment of Children Older Than Two Years of Age With X-Linked Severe Combined Immunodeficiency (XSCID)

  • NCT01608152 · 40 participants

    Development of a Video Game for the Improvement of Outcomes in Stem Cell Transplant Survivors

  • NCT01668082 · 40 participants · NA

    An Investigation of Brain Tumor Metabolism in Patients Undergoing Surgical Resection

  • NCT02015013 · 40 participants · Phase 2

    Hematopoietic Stem Cell Mobilization in Idiopathic CD4 Lymphocytopenia Patients and Healthy Controls for the Study of T Cell Maturation and Trafficking in Murine Models

Similar registry start date

  • NCT05962346 · started 2026-12 · NA

    Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia

  • NCT07125183 · started 2026-12 · Phase 2

    Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma

  • NCT07292298 · started 2026-11 · Phase 2

    Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates

  • NCT04263285 · started 2026-10 · NA

    Treatment of Depression Post-SCI

Source: ClinicalTrials.gov NCT07217054, the US trial registry maintained by the National Library of Medicine. NCT07217054 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.