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NCT07419763 · ClinicalTrials.gov registry record · NA
Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste
A NA study of Dental Caries, sponsored by Church & Dwight Company.
- Completed
- Registry status
- NA
- Development phase
- 30
- Enrollment target
- 1
- Study location
NCT07419763: Completed NA study of Dental Caries, sponsored by Church & Dwight Company.
NCT07419763 is a NA study of Dental Caries that has completed, run by Church & Dwight Company. The registered enrollment target is 30 participants, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (96% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07419763, a NA study of Dental Caries, has completed, sponsored by Church & Dwight Company.
- COMPLETED
- Registry status
- NA
- Development phase
- 30 participants
- Enrollment target
- 1
- Study location
Study Summary
This single-center, randomized, double-blind, three-period crossover in situ study evaluated the enamel remineralization potential and fluoride bioavailability of three dentifrices: a fluoride-free negative control, a positive control with 0.243% sodium fluoride, and an investigational dentifrice containing 0.243% sodium fluoride, 5.0% potassium nitrate (KNO₃), and 20% sodium bicarbonate. Adult subjects wore acrylic palatal appliances containing demineralized enamel specimens for three 7-day treatment periods, each preceded by a 5-day fluoride-free washout. Primary outcomes were percent surface microhardness recovery (%SMHR) and enamel fluoride concentration.
Conditions Studied
Interventions
- DRUG Active Comparator
- DRUG Negative Control Toothpaste
- DRUG Test toothpaste
Study Locations (1)
Indiana
- Therametric Technologies, Inc. - Noblesville
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-04-15 |
| Est. Completion | 2025-06-10 |
| Phase | NA |
What the finished NCT07419763 record still lists
NCT07419763 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 30 participants, a relatively small participant target, below the 721-participant average among 30 other Dental Caries trials with a reported enrollment target (96% lower).
The record links to 1 condition, with Dental Caries appearing as the primary indexed condition, and to 3 interventions - of which Active Comparator is the first listed.
NCT07419763 reports a single indexed study location in Indiana.
Frequently Asked Questions
What is clinical trial NCT07419763 about?
NCT07419763 is a clinical study titled "Intra Oral Appliance (IOA) Model Evaluating the Efficacy of Sensitive Toothpaste". This single-center, randomized, double-blind, three-period crossover in situ study evaluated the enamel remineralization potential and fluoride bioavailability of three dentifrices: a fluoride-free negative control, a positive control with 0.243% sodium fluoride, and an investigational dentifrice co...
What is the current status of trial NCT07419763?
This trial is currently completed. It is a NA study. The enrollment target is 30 participants. The study started on 2025-04-15. Estimated completion is 2025-06-10.
What conditions does trial NCT07419763 study?
This clinical trial studies the following conditions: Dental Caries.
What interventions are being tested in trial NCT07419763?
The interventions under investigation include: Active Comparator (DRUG), Negative Control Toothpaste (DRUG), Test toothpaste (DRUG).
Who is sponsoring clinical trial NCT07419763?
This trial is sponsored by Church & Dwight Company, which has 19 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07419763 being conducted?
This trial has 1 study location across Indiana. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07419763's enrollment target sits among peer trials
30 25th of 30 higher than 4 of 30 other Dental Caries trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Dental Caries trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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