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NCT07407777 · ClinicalTrials.gov registry record · NA

Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)

A NA study of Gastrointestinal Discomfort and Digestive Well Being, sponsored by Koralo.

Recruiting
Registry status
NA
Development phase
80
Enrollment target
1
Study location

NCT07407777: Recruiting NA study of Gastrointestinal Discomfort and Digestive Well Being, sponsored by Koralo.

NCT07407777 is a NA study of Gastrointestinal Discomfort and Digestive Well Being that is actively recruiting participants, run by Koralo. The registered enrollment target is 80 participants, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07407777, a NA study of Gastrointestinal Discomfort and Digestive Well Being, is actively recruiting participants, sponsored by Koralo.

RECRUITING
Registry status
NA
Development phase
80 participants
Enrollment target
1
Study location

Study Summary

The purpose of the study is to evaluate the gut-related well-being and mood effects of a food ingredient obtained from the co-fermentation of oyster mushroom mycelium (Pleurotus pulmonarius), microalgae (Chlorella vulgaris), and bamboo fibre in healthy adults (aged 18+) experiencing minor gastrointestinal discomfort during an intervention period of 30 days. The participants will be allocated into two unbalanced groups to determine relationships between the measurable outcomes and the dose levels at three different time points: start of the study (baseline), 15 days (middle), and 30 days (end-point), during which participants will be asked to complete GSRS and POMS-2-SF questionnaire

Primary Outcome

The primary outcome is the change in gastrointestinal symptom severity as measured by the Gastrointestinal Symptom Rating Scale (GSRS). The GSRS is a validated self-report questionnaire assessing the severity of common gastrointestinal symptoms. Change in total GSRS score will be evaluated over the course of the 30-day intervention to assess the effect of the investigational food ingredient on gut-related well-being.

Interventions

  • DIETARY_SUPPLEMENT Food ingredient of oyster mushroom mycelium (Pleurotus pulmonarius) and microalgae (Chlorella vulgaris)

Study Locations (1)

California

  • Alethios, Inc. - San Francisco

Trial Details

FieldValue
Enrollment Target 80 participants
Start Date 2026-01-19
Est. Completion 2026-05-19
Phase NA
Koralo

1 total trials

What NCT07407777 shows while recruiting

NCT07407777 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 80 participants, a relatively small participant target, below the 1,404-participant average among 58,714 other NA trials with a reported enrollment target (94% lower).

The record links to 3 conditions, with Gastrointestinal Discomfort appearing as the primary indexed condition, and to 1 intervention - of which Food ingredient of oyster mushroom mycelium (Pleurotus pulmonarius) and microalgae (Chlorella vulgaris) is the first listed.

NCT07407777 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT07407777 about?

NCT07407777 is a clinical study titled "Evaluation of Gut-Related Well-Being and Mood Effects of a Daily Nutritional Food Ingredient From the Co-Fermentation of Fungal Mycelium (Pleurotus Pulmonarius) and Microalgae (Chlorella Vulgaris)". The purpose of the study is to evaluate the gut-related well-being and mood effects of a food ingredient obtained from the co-fermentation of oyster mushroom mycelium (Pleurotus pulmonarius), microalgae (Chlorella vulgaris), and bamboo fibre in healthy adults (aged 18+) experiencing minor gastrointe...

What is the current status of trial NCT07407777?

This trial is currently recruiting. It is a NA study. The enrollment target is 80 participants. The study started on 2026-01-19. Estimated completion is 2026-05-19.

What conditions does trial NCT07407777 study?

This clinical trial studies the following conditions: Gastrointestinal Discomfort, Digestive Well Being, Gut-related Symptoms.

What interventions are being tested in trial NCT07407777?

The interventions under investigation include: Food ingredient of oyster mushroom mycelium (Pleurotus pulmonarius) and microalgae (Chlorella vulgaris) (DIETARY_SUPPLEMENT).

Who is sponsoring clinical trial NCT07407777?

This trial is sponsored by Koralo, which has 1 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07407777 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

How this trial's enrollment target compares

Where NCT07407777's enrollment target sits among peer trials

80 994th of 2000 higher than 941 of 2,000 other NA trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other NA trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07407777, the US trial registry maintained by the National Library of Medicine. NCT07407777 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.