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NCT07401875 · ClinicalTrials.gov registry record · Phase 1

A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)

A Phase 1 study, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 1
Development phase
35
Enrollment target

NCT07401875: Recruiting Phase 1 study, sponsored by M.D. Anderson Cancer Center.

NCT07401875 is a Phase 1 study that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 35 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07401875, a Phase 1 study, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 1
Development phase
35 participants
Enrollment target

Study Summary

To find out if the combination of HC-7366 and nivolumab (with or without ipilimumab) can help to control ccRCC. The

Interventions

  • DRUG Nivolumab
  • DRUG HC-7366
  • DRUG ipilimumab

Trial Details

FieldValue
Enrollment Target 35 participants
Start Date 2026-03-24
Est. Completion 2029-11-30
Phase Phase 1

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT07401875

The ClinicalTrials.gov registry entry for NCT07401875 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 35 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 3 interventions - of which Nivolumab is the first listed.

NCT07401875 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07401875 about?

NCT07401875 is a clinical study titled "A Phase 1b Study of HC-7366, an Agonist of ISR With Immunotherapy in Kidney Cancer (SHARK)". To find out if the combination of HC-7366 and nivolumab (with or without ipilimumab) can help to control ccRCC. The

What is the current status of trial NCT07401875?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 35 participants. The study started on 2026-03-24. Estimated completion is 2029-11-30.

What interventions are being tested in trial NCT07401875?

The interventions under investigation include: Nivolumab (DRUG), HC-7366 (DRUG), ipilimumab (DRUG).

Who is sponsoring clinical trial NCT07401875?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.