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NCT07343596 · ClinicalTrials.gov registry record · NA
Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery
A NA study of Oral Cavity Cancer, sponsored by University of Wisconsin, Madison.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07343596: Recruiting NA study of Oral Cavity Cancer, sponsored by University of Wisconsin, Madison.
NCT07343596 is a NA study of Oral Cavity Cancer that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 20 participants, below the 225-participant average among 12 other Oral Cavity Cancer trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07343596, a NA study of Oral Cavity Cancer, is actively recruiting participants, sponsored by University of Wisconsin, Madison.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
The goal of this clinical trial is to study whether researchers can create a patient-specific tumor system, called a culture vessel, in a timely manner and determine if it can predict how someone will respond to a specific therapy. Participants will: * Undergo a research biopsy * Take pembrolizumab per standard of care prior to surgery
Primary Outcome
Identification of pathways that are activated in samples showing substantial response versus those that do not. Gene expression changes will be evaluated through mRNA sequencing and bioinformatic analysis.
Conditions Studied
Interventions
- BIOLOGICAL Pembrolizumab
- DEVICE Patient-Specific Culture Vessel
Study Locations (1)
Wisconsin
- University of Wisconsin - Madison - Madison
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2026-03 |
| Est. Completion | 2027-12 |
| Phase | NA |
What NCT07343596 shows while recruiting
NCT07343596 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 225-participant average among 12 other Oral Cavity Cancer trials with a reported enrollment target (91% lower).
The record links to 1 condition, with Oral Cavity Cancer appearing as the primary indexed condition, and to 2 interventions - of which Pembrolizumab is the first listed.
NCT07343596 reports a single indexed study location in Wisconsin.
Frequently Asked Questions
What is clinical trial NCT07343596 about?
NCT07343596 is a clinical study titled "Study to Identify Biomarkers of Oral Cavity Cancer Response to Neoadjuvant Immunotherapy Prior to Definitive Surgery". The goal of this clinical trial is to study whether researchers can create a patient-specific tumor system, called a culture vessel, in a timely manner and determine if it can predict how someone will respond to a specific therapy. Participants will: * Undergo a research biopsy * Take pembrolizuma...
What is the current status of trial NCT07343596?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2026-03. Estimated completion is 2027-12.
What conditions does trial NCT07343596 study?
This clinical trial studies the following conditions: Oral Cavity Cancer.
What interventions are being tested in trial NCT07343596?
The interventions under investigation include: Pembrolizumab (BIOLOGICAL), Patient-Specific Culture Vessel (DEVICE).
Who is sponsoring clinical trial NCT07343596?
This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07343596 being conducted?
This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Oral Cavity Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07343596's enrollment target sits among peer trials
20 12th of 12 the lowest of 12 other Oral Cavity Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Oral Cavity Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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