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NCT07339085 · ClinicalTrials.gov registry record · NA
Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis
A NA study of Metastatic Malignant Neoplasm in the Brain and Malignant Brain Neoplasm, sponsored by Jonsson Comprehensive Cancer Center.
- Recruiting
- Registry status
- NA
- Development phase
- 42
- Enrollment target
- 1
- Study location
NCT07339085 is a NA study of Metastatic Malignant Neoplasm in the Brain and Malignant Brain Neoplasm that is actively recruiting participants, run by Jonsson Comprehensive Cancer Center. The registered enrollment target is 42 participants, below the 87-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (52% lower). The trial reports 1 study location across 1 state.
The verdict
NCT07339085, a NA study of Metastatic Malignant Neoplasm in the Brain and Malignant Brain Neoplasm, is actively recruiting participants, sponsored by Jonsson Comprehensive Cancer Center.
- RECRUITING
- Registry status
- NA
- Development phase
- 42 participants
- Enrollment target
- 1
- Study location
Study Summary
This clinical trial studies whether advanced magnetic resonance imaging (MRI) techniques, including diffusion-relaxation correlation spectrum imaging (DR-CSI) and sodium imaging, can be used to identify the difference between brain tumors that come back after a period of improvement (recurrent) and treatment-related tissue damage (radiation necrosis \[RN\]). Radiation therapy is often used in the treatment of brain tumors. Radiation treatment response can be difficult to assess and is usually done using conventional MRI, which uses radio waves and a powerful magnet linked to a computer to create detailed pictures of areas inside the body. Current imaging techniques have a limited ability to identify the difference between recurrent brain tumor and RN due to their similar appearance on conventional MRI and overlapping clinical presentation. This makes it hard for doctors to plan the best way to treat these tumors. DR-CSI is a new MRI technique with the potential to detect microscopic tissue components with different characteristics. Sodium imaging is an MRI technique that estimates the total sodium concentration in the obtained images. It may be able to identify the small structures within the tissue of brain tumors. Advanced MRI techniques like DR-CSI and sodium imaging may be effective in identifying the difference between recurrent brain tumors and RN.
Conditions Studied
Interventions
- PROCEDURE Biospecimen Collection
- PROCEDURE Magnetic Resonance Imaging
- PROCEDURE Advanced Magnetic Resonance Imaging
Study Locations (1)
California
- UCLA / Jonsson Comprehensive Cancer Center - Los Angeles
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 42 participants |
| Start Date | 2025-08-28 |
| Est. Completion | 2030-07-30 |
| Phase | NA |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07339085
The ClinicalTrials.gov registry entry for NCT07339085 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 42 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 87-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (52% lower). The listed sponsor is Jonsson Comprehensive Cancer Center, which has 321 total studies on file at ClinicalTrials.gov.
The record links to 2 conditions, with Metastatic Malignant Neoplasm in the Brain appearing as the primary indexed condition, and to 3 interventions - of which Biospecimen Collection is the first listed.
NCT07339085 reports 1 study location spanning 1 distinct geographic area - top geographies include California.
Frequently Asked Questions
What is clinical trial NCT07339085 about?
NCT07339085 is a clinical study titled "Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis". This clinical trial studies whether advanced magnetic resonance imaging (MRI) techniques, including diffusion-relaxation correlation spectrum imaging (DR-CSI) and sodium imaging, can be used to identify the difference between brain tumors that come back after a period of improvement (recurrent) and ...
What is the current status of trial NCT07339085?
This trial is currently recruiting. It is a NA study. The enrollment target is 42 participants. The study started on 2025-08-28. Estimated completion is 2030-07-30.
What conditions does trial NCT07339085 study?
This clinical trial studies the following conditions: Metastatic Malignant Neoplasm in the Brain, Malignant Brain Neoplasm.
What interventions are being tested in trial NCT07339085?
The interventions under investigation include: Biospecimen Collection (PROCEDURE), Magnetic Resonance Imaging (PROCEDURE), Advanced Magnetic Resonance Imaging (PROCEDURE).
Who is sponsoring clinical trial NCT07339085?
This trial is sponsored by Jonsson Comprehensive Cancer Center, which has 321 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07339085 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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