Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.
NCT04062305 · ClinicalTrials.gov registry record · NA
nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex
A NA study of Metastatic Malignant Neoplasm in the Brain and Radiation Therapy Recipient, sponsored by M.D. Anderson Cancer Center.
- Active
- Registry status
- NA
- Development phase
- 22
- Enrollment target
- 1
- Study location
NCT04062305: Active NA study of Metastatic Malignant Neoplasm in the Brain and Radiation Therapy Recipient, sponsored by M.D. Anderson Cancer Center.
NCT04062305 is a NA study of Metastatic Malignant Neoplasm in the Brain and Radiation Therapy Recipient that is active but no longer recruiting, run by M.D. Anderson Cancer Center. The registered enrollment target is 22 participants, below the 88-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (75% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT04062305, a NA study of Metastatic Malignant Neoplasm in the Brain and Radiation Therapy Recipient, is active but no longer recruiting, sponsored by M.D. Anderson Cancer Center.
- ACTIVE NOT RECRUITING
- Registry status
- NA
- Development phase
- 22 participants
- Enrollment target
- 1
- Study location
Study Summary
This trial studies how well nTMS works in planning for stereotactic radiosurgery in patients with brain metastases in the motor cortex. Stereotactic radiosurgery is a type of radiation therapy that delivers high doses of radiation, which can sometimes lead to damage occurring to the brain and surrounding areas. The motor cortex (the part of the nervous system that controls muscle movement), however, currently has no radiation dose limit. nTMS is a non-invasive tool that uses sensors on a patient's muscle to trace the location in their brain that controls that muscle and is currently used by doctors to decide where to operate so as not to damage the motor nerves. nTMS may effectively help plan radiation treatment using SRS and help doctors decide on how much radiation can be used on motor nerves.
Primary Outcome
Will be determined to be operationally feasible on a patient if the images and data obtained from nTMS for the patient provide useful information to the radiation oncologist and if the radiation oncologist determines that this additional information would improve patient care. Will deem the use of nTMS to be operationally feasible overall if it is deemed operationally feasible on an underlying proportion of at least 90% potentially consented patients. Will calculate the proportions of operationa
Conditions Studied
Interventions
- OTHER Quality-of-Life Assessment
- OTHER Questionnaire Administration
- BEHAVIORAL Hand Function Test
- PROCEDURE Navigated Transcranial Magnetic Stimulation
Study Locations (1)
Texas
- M D Anderson Cancer Center - Houston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 22 participants |
| Start Date | 2019-09-09 |
| Est. Completion | 2027-05-06 |
| Phase | NA |
What the registry record for NCT04062305 still lists
NCT04062305 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 22 participants, a relatively small participant target, below the 88-participant average among 43 other Metastatic Malignant Neoplasm in the Brain trials with a reported enrollment target (75% lower).
The record links to 2 conditions, with Metastatic Malignant Neoplasm in the Brain appearing as the primary indexed condition, and to 4 interventions - of which Quality-of-Life Assessment is the first listed.
NCT04062305 reports a single indexed study location in Texas.
Frequently Asked Questions
What is clinical trial NCT04062305 about?
NCT04062305 is a clinical study titled "nTMS in Planning Stereotactic Radiosurgery in Patients With Brain Metastases in the Motor Cortex". This trial studies how well nTMS works in planning for stereotactic radiosurgery in patients with brain metastases in the motor cortex. Stereotactic radiosurgery is a type of radiation therapy that delivers high doses of radiation, which can sometimes lead to damage occurring to the brain and surrou...
What is the current status of trial NCT04062305?
This trial is currently active not recruiting. It is a NA study. The enrollment target is 22 participants. The study started on 2019-09-09. Estimated completion is 2027-05-06.
What conditions does trial NCT04062305 study?
This clinical trial studies the following conditions: Metastatic Malignant Neoplasm in the Brain, Radiation Therapy Recipient.
What interventions are being tested in trial NCT04062305?
The interventions under investigation include: Quality-of-Life Assessment (OTHER), Questionnaire Administration (OTHER), Hand Function Test (BEHAVIORAL), Navigated Transcranial Magnetic Stimulation (PROCEDURE).
Who is sponsoring clinical trial NCT04062305?
This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT04062305 being conducted?
This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Metastatic Malignant Neoplasm in the Brain
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT04062305's enrollment target sits among peer trials
22 33rd of 43 higher than 10 of 43 other Metastatic Malignant Neoplasm in the Brain trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Metastatic Malignant Neoplasm in the Brain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
-
Advanced Magnetic Resonance Imaging for the Identification of Recurrent Brain Tumors and Radiation Necrosis
RECRUITING · NA
-
Neurocognition in Patients With Multiple Brain Metastases Treated With Radiosurgery
RECRUITING · NA
-
Electrocorticography in Mapping Functional Brain Areas During Surgery in Patients With Brain Tumors
RECRUITING · NA
-
Feasibility of Intraoperative Microdialysis During Neurosurgery for Central Nervous System Malignancies
RECRUITING · NA
-
Mind-Body Intervention in Glioma Couples
ACTIVE NOT RECRUITING · NA
-
Ferumoxytol in Improving MR Imaging in Patients With High-Grade Brain Tumors or Cerebral Metastases
COMPLETED · NA
Nationwide trials with similar profiles
Cross-condition peers matched on enrollment target and registry start date, not the same-condition list above.
Similar enrollment target
- NCT02508038 · 22 participants · Phase 1
Alpha/Beta CD19+ Depleted Haploidentical Transplantation + Zometa for Pediatric Hematologic Malignancies and Solid Tumors
- NCT03099356 · 22 participants · Phase 2
Cyclophosphamide and Sirolimus for the Treatment of Metastatic, RAI-refractory, Differentiated Thyroid Cancer
- NCT03676647 · 22 participants
Diagnostic DNA Methylation Signature in Diagnosing Thyroid Cancer After Fine-Needle Aspiration in Patients With Thyroid Nodules
- NCT04569591 · 22 participants · NA
DDAVP for Pituitary Adenoma
Similar registry start date
- NCT05962346 · started 2026-12 · NA
Fetal Endoscopic Tracheal Occlusion for Congenital Diaphragmatic Hernia
- NCT07125183 · started 2026-12 · Phase 2
Study on Efficacy and Tolerability of Weekly Doxorubicin in Elderly Patients With Advanced or Metastatic Leiomyosarcoma
- NCT07292298 · started 2026-11 · Phase 2
Phase 2 Single-Arm Rectal Cancer Brachytherapy for Patients With Low-Lying Residual Adenocarcinoma After Total Neoadjuvant Therapy to Improve Organ Preservation Rates
- NCT04263285 · started 2026-10 · NA
Treatment of Depression Post-SCI