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NCT07329972 · ClinicalTrials.gov registry record · Phase 1

A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants

A Phase 1 study of Healthy Volunteers, sponsored by Genentech.

Recruiting
Registry status
Phase 1
Development phase
48
Enrollment target
2
Study locations

NCT07329972 is a Phase 1 study of Healthy Volunteers that is actively recruiting participants, run by Genentech. The registered enrollment target is 48 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 2 states.

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The verdict

NCT07329972, a Phase 1 study of Healthy Volunteers, is actively recruiting participants, sponsored by Genentech.

RECRUITING
Registry status
Phase 1
Development phase
48 participants
Enrollment target
2
Study locations

Study Summary

This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.

Conditions Studied

Healthy Volunteers

Interventions

  • DRUG Rabeprazole
  • DRUG ZN-A-1041 Formulation 1
  • DRUG ZN-A-1041 Formulation 2

Study Locations (2)

Florida

  • Daytona Beach Clinical Rsch Unit - Daytona Beach

Texas

  • Fortrea Clinical Research Unit - Dallas - Dallas

Trial Details

FieldValue
Enrollment Target 48 participants
Start Date 2025-11-21
Est. Completion 2026-08-12
Phase Phase 1

Sponsor

Genentech

332 total trials

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What the Registry Record Tells You About NCT07329972

The ClinicalTrials.gov registry entry for NCT07329972 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 48 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (90% lower). The listed sponsor is Genentech, which has 332 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 3 interventions - of which Rabeprazole is the first listed.

NCT07329972 reports 2 study locations spanning 2 distinct geographic areas - top geographies include Florida, Texas.

Frequently Asked Questions

What is clinical trial NCT07329972 about?

NCT07329972 is a clinical study titled "A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants". This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.

What is the current status of trial NCT07329972?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2025-11-21. Estimated completion is 2026-08-12.

What conditions does trial NCT07329972 study?

This clinical trial studies the following conditions: Healthy Volunteers.

What interventions are being tested in trial NCT07329972?

The interventions under investigation include: Rabeprazole (DRUG), ZN-A-1041 Formulation 1 (DRUG), ZN-A-1041 Formulation 2 (DRUG).

Who is sponsoring clinical trial NCT07329972?

This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07329972 being conducted?

This trial has 2 study locations across Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.