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NCT07329972 · ClinicalTrials.gov registry record · Phase 1
A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants
A Phase 1 study of Healthy Volunteers, sponsored by Genentech.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 48
- Enrollment target
- 2
- Study locations
NCT07329972: Recruiting Phase 1 study of Healthy Volunteers, sponsored by Genentech.
NCT07329972 is a Phase 1 study of Healthy Volunteers that is actively recruiting participants, run by Genentech. The registered enrollment target is 48 participants, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (90% lower). The trial reports 2 study locations across 2 states. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07329972, a Phase 1 study of Healthy Volunteers, is actively recruiting participants, sponsored by Genentech.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 48 participants
- Enrollment target
- 2
- Study locations
Study Summary
This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.
Conditions Studied
Interventions
- DRUG Rabeprazole
- DRUG ZN-A-1041 Formulation 1
- DRUG ZN-A-1041 Formulation 2
Study Locations (2)
Florida
- Daytona Beach Clinical Rsch Unit - Daytona Beach
Texas
- Fortrea Clinical Research Unit - Dallas - Dallas
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 48 participants |
| Start Date | 2025-11-21 |
| Est. Completion | 2026-08-12 |
| Phase | Phase 1 |
What NCT07329972 shows while recruiting
NCT07329972 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 48 participants, a relatively small participant target, below the 482-participant average among 283 other Healthy Volunteers trials with a reported enrollment target (90% lower).
The record links to 1 condition, with Healthy Volunteers appearing as the primary indexed condition, and to 3 interventions - of which Rabeprazole is the first listed.
NCT07329972 reports a single indexed study location in Florida, Texas.
Frequently Asked Questions
What is clinical trial NCT07329972 about?
NCT07329972 is a clinical study titled "A Study to Evaluate the Effect of Food and Proton Pump Inhibitor on the Pharmacokinetics of ZN-A-1041 in Healthy Participants". This study is a phase 1, open-label, randomized, four-period crossover study to evaluate the effect of food and rabeprazole on the ZN-A-1041 tablet formulation in healthy male and female participants.
What is the current status of trial NCT07329972?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 48 participants. The study started on 2025-11-21. Estimated completion is 2026-08-12.
What conditions does trial NCT07329972 study?
This clinical trial studies the following conditions: Healthy Volunteers.
What interventions are being tested in trial NCT07329972?
The interventions under investigation include: Rabeprazole (DRUG), ZN-A-1041 Formulation 1 (DRUG), ZN-A-1041 Formulation 2 (DRUG).
Who is sponsoring clinical trial NCT07329972?
This trial is sponsored by Genentech, which has 332 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07329972 being conducted?
This trial has 2 study locations across Florida, Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy Volunteers
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07329972's enrollment target sits among peer trials
48 142nd of 283 higher than 140 of 283 other Healthy Volunteers trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy Volunteers trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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