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NCT07303998 · ClinicalTrials.gov registry record · NA
Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients
A NA study of Alzheimers Disease and Other Dementias, sponsored by University of Arizona.
- Recruiting
- Registry status
- NA
- Development phase
- 40
- Enrollment target
- 1
- Study location
NCT07303998: Recruiting NA study of Alzheimers Disease and Other Dementias, sponsored by University of Arizona.
NCT07303998 is a NA study of Alzheimers Disease and Other Dementias that is actively recruiting participants, run by University of Arizona. The registered enrollment target is 40 participants, below the 3,926-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07303998, a NA study of Alzheimers Disease and Other Dementias, is actively recruiting participants, sponsored by University of Arizona.
- RECRUITING
- Registry status
- NA
- Development phase
- 40 participants
- Enrollment target
- 1
- Study location
Study Summary
This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and online chair yoga (OCY) to manage chronic knee pain in older adults with Alzheimer's Disease and Related Dementias (ADRD). Chronic knee pain is prevalent among individuals with ADRD and is often underdiagnosed and undertreated, contributing to neuropsychiatric symptoms, reduced quality of life, and increased caregiver burden. Current pharmacological options, such as opioids, pose risks of adverse events in this population. tDCS is a safe, noninvasive technique that uses low-intensity electrical current to modulate brain activity and may improve pain perception by targeting central mechanisms. Chair yoga is a mind-body intervention shown to improve pain and mood in older adults, including those with dementia. This study proposes that combining tDCS and OCY may have synergistic benefits in reducing pain and enhancing function. Participants will include older adults aged 60+ with mild to moderate ADRD and chronic knee pain, along with their caregivers. Over four weeks, participants will complete 14 supervised sessions of combined tDCS and OCY at home. Outcomes include feasibility, satisfaction, pain intensity, pain interference, neuropsychiatric symptoms, sleep disturbance, cognitive function, mobility, and quality of life. Neurophysiological measures (e.g., fNIRS, EEG, HF-HRV) will also be assessed to explore underlying mechanisms. This study seeks to lay the foundation for future large-scale randomized controlled trials of home-based nonpharmacological interventions for chronic pain in ADRD.
Primary Outcome
Clinical pain intensity will be measured by asking participants to rate their knee pain over the last 24 hours between 0 (no pain) - 10 (worst pain imaginable). The NRS has a reported Cronbach's alpha coefficient of ≥ 0.8 and is a reliable way for measuring knee pain in adults with knee osteoarthritis.
Conditions Studied
Interventions
- DEVICE Active tDCS paired with active online chair yoga
Study Locations (1)
Arizona
- University of Arizona College of Nursing - Tucson
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 40 participants |
| Start Date | 2025-03-04 |
| Est. Completion | 2026-08-30 |
| Phase | NA |
What NCT07303998 shows while recruiting
NCT07303998 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 40 participants, a relatively small participant target, below the 3,926-participant average among 147 other Alzheimers Disease trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Alzheimers Disease appearing as the primary indexed condition, and to 1 intervention - of which Active tDCS paired with active online chair yoga is the first listed.
NCT07303998 reports a single indexed study location in Arizona.
Frequently Asked Questions
What is clinical trial NCT07303998 about?
NCT07303998 is a clinical study titled "Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients". This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and online chair yoga (OCY) to manage chronic knee pain in older adults with Alzheimer's Disease and Related ...
What is the current status of trial NCT07303998?
This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-03-04. Estimated completion is 2026-08-30.
What conditions does trial NCT07303998 study?
This clinical trial studies the following conditions: Alzheimers Disease, Other Dementias.
What interventions are being tested in trial NCT07303998?
The interventions under investigation include: Active tDCS paired with active online chair yoga (DEVICE).
Who is sponsoring clinical trial NCT07303998?
This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07303998 being conducted?
This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Where NCT07303998's enrollment target sits among peer trials
40 106th of 147 higher than 39 of 147 other Alzheimers Disease trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Alzheimers Disease trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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