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NCT07303998 · ClinicalTrials.gov registry record · NA

Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients

A NA study of Alzheimer&Amp;#39;s Disease and Other Dementias, sponsored by University of Arizona.

Recruiting
Registry status
NA
Development phase
40
Enrollment target
1
Study location

NCT07303998 is a NA study of Alzheimer&Amp;#39;s Disease and Other Dementias that is actively recruiting participants, run by University of Arizona. The registered enrollment target is 40 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07303998, a NA study of Alzheimer&Amp;#39;s Disease and Other Dementias, is actively recruiting participants, sponsored by University of Arizona.

RECRUITING
Registry status
NA
Development phase
40 participants
Enrollment target
1
Study location

Study Summary

This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and online chair yoga (OCY) to manage chronic knee pain in older adults with Alzheimer's Disease and Related Dementias (ADRD). Chronic knee pain is prevalent among individuals with ADRD and is often underdiagnosed and undertreated, contributing to neuropsychiatric symptoms, reduced quality of life, and increased caregiver burden. Current pharmacological options, such as opioids, pose risks of adverse events in this population. tDCS is a safe, noninvasive technique that uses low-intensity electrical current to modulate brain activity and may improve pain perception by targeting central mechanisms. Chair yoga is a mind-body intervention shown to improve pain and mood in older adults, including those with dementia. This study proposes that combining tDCS and OCY may have synergistic benefits in reducing pain and enhancing function. Participants will include older adults aged 60+ with mild to moderate ADRD and chronic knee pain, along with their caregivers. Over four weeks, participants will complete 14 supervised sessions of combined tDCS and OCY at home. Outcomes include feasibility, satisfaction, pain intensity, pain interference, neuropsychiatric symptoms, sleep disturbance, cognitive function, mobility, and quality of life. Neurophysiological measures (e.g., fNIRS, EEG, HF-HRV) will also be assessed to explore underlying mechanisms. This study seeks to lay the foundation for future large-scale randomized controlled trials of home-based nonpharmacological interventions for chronic pain in ADRD.

Interventions

  • DEVICE Active tDCS paired with active online chair yoga

Study Locations (1)

Arizona

  • University of Arizona College of Nursing - Tucson

Trial Details

FieldValue
Enrollment Target 40 participants
Start Date 2025-03-04
Est. Completion 2026-08-30
Phase NA

Sponsor

University of Arizona

349 total trials

What the Registry Record Tells You About NCT07303998

The ClinicalTrials.gov registry entry for NCT07303998 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 40 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is University of Arizona, which has 349 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Alzheimer&Amp;#39;s Disease appearing as the primary indexed condition, and to 1 intervention - of which Active tDCS paired with active online chair yoga is the first listed.

NCT07303998 reports 1 study location spanning 1 distinct geographic area - top geographies include Arizona.

Frequently Asked Questions

What is clinical trial NCT07303998 about?

NCT07303998 is a clinical study titled "Remote tDCS and Chair Yoga for Chronic Knee Pain in Alzheimer's Patients". This study aims to evaluate the feasibility, acceptability, and preliminary effects of a home-based, remotely supervised intervention combining transcranial direct current stimulation (tDCS) and online chair yoga (OCY) to manage chronic knee pain in older adults with Alzheimer's Disease and Related ...

What is the current status of trial NCT07303998?

This trial is currently recruiting. It is a NA study. The enrollment target is 40 participants. The study started on 2025-03-04. Estimated completion is 2026-08-30.

What conditions does trial NCT07303998 study?

This clinical trial studies the following conditions: Alzheimer&Amp;#39;s Disease, Other Dementias.

What interventions are being tested in trial NCT07303998?

The interventions under investigation include: Active tDCS paired with active online chair yoga (DEVICE).

Who is sponsoring clinical trial NCT07303998?

This trial is sponsored by University of Arizona, which has 349 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07303998 being conducted?

This trial has 1 study location across Arizona. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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