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NCT06484244 · ClinicalTrials.gov registry record · NA
Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease
A NA study of Mild Cognitive Impairment and Alzheimers Disease, sponsored by Emory University.
- Recruiting
- Registry status
- NA
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT06484244: Recruiting NA study of Mild Cognitive Impairment and Alzheimers Disease, sponsored by Emory University.
NCT06484244 is a NA study of Mild Cognitive Impairment and Alzheimers Disease that is actively recruiting participants, run by Emory University. The registered enrollment target is 10 participants, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT06484244, a NA study of Mild Cognitive Impairment and Alzheimers Disease, is actively recruiting participants, sponsored by Emory University.
- RECRUITING
- Registry status
- NA
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor impairments. It is also an important therapeutic target for exercise-based interventions to improve walking function. The overall goal of this study is to understand the effects of MCI and AD on locomotor adaptation and walking function.
Primary Outcome
Locomotor adaptation is the ability to adjust stepping movements to changing environmental demands via trial-and-error processing. Step length symmetry data from the split-belt phase will be used to evaluate each individual's locomotor adaptation magnitude capacity by assessing the peak step length symmetry in the early adaptation period.
Conditions Studied
Interventions
- OTHER 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation
Study Locations (1)
Georgia
- Emory Rehabilitation Hospital - Atlanta
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2025-07-22 |
| Est. Completion | 2026-12-31 |
| Phase | NA |
What NCT06484244 shows while recruiting
NCT06484244 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 10 participants, a relatively small participant target, below the 1,270-participant average among 205 other Mild Cognitive Impairment trials with a reported enrollment target (99% lower).
The record links to 2 conditions, with Mild Cognitive Impairment appearing as the primary indexed condition, and to 1 intervention - of which 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation is the first listed.
NCT06484244 reports a single indexed study location in Georgia.
Frequently Asked Questions
What is clinical trial NCT06484244 about?
NCT06484244 is a clinical study titled "Locomotion Adaptation Deficits in Older Adults With Mild Cognitive Impairment and Alzheimers Disease". In people with Mild Cognitive Impairment (MCI) and Alzheimer's Disease (AD), reduced capacity for locomotor adaptation is a fundamental but poorly understood mechanism that can be a sensitive biomarker of cognitive-motor impairments. It is also an important therapeutic target for exercise-based inte...
What is the current status of trial NCT06484244?
This trial is currently recruiting. It is a NA study. The enrollment target is 10 participants. The study started on 2025-07-22. Estimated completion is 2026-12-31.
What conditions does trial NCT06484244 study?
This clinical trial studies the following conditions: Mild Cognitive Impairment, Alzheimers Disease.
What interventions are being tested in trial NCT06484244?
The interventions under investigation include: 5 Sessions of Split-belt Treadmill-based Locomotor Adaptation (OTHER).
Who is sponsoring clinical trial NCT06484244?
This trial is sponsored by Emory University, which has 1,208 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT06484244 being conducted?
This trial has 1 study location across Georgia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
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Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT06484244's enrollment target sits among peer trials
10 199th of 205 higher than 6 of 205 other Mild Cognitive Impairment trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Mild Cognitive Impairment trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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