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NCT07300241 · ClinicalTrials.gov registry record · Phase 1
Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma
A Phase 1 study of Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma, sponsored by Neomorph.
- Recruiting
- Registry status
- Phase 1
- Development phase
- 30
- Enrollment target
- 7
- Study locations
NCT07300241 is a Phase 1 study of Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma that is actively recruiting participants, run by Neomorph. The registered enrollment target is 30 participants, below the 243-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (88% lower). The trial reports 7 study locations across 5 states.
The verdict
NCT07300241, a Phase 1 study of Renal Cell Carcinoma and Clear Cell Renal Cell Carcinoma, is actively recruiting participants, sponsored by Neomorph.
- RECRUITING
- Registry status
- Phase 1
- Development phase
- 30 participants
- Enrollment target
- 7
- Study locations
Study Summary
The NEO-811-101 study is an open-label, first-in-human, Phase 1/2 dose escalation and expansion study of NEO-811 for subjects with locally advanced or metastatic non-resectable clear cell renal cell carcinoma. The study will test NEO-811 initially as a monotherapy.
Conditions Studied
Interventions
- DRUG NEO-811
Study Locations (7)
New York
- NEO-811 Long Island Site - Lake Success
- NEO-811-101 NYC Site - New York
Texas
- NEO-811 Dallas Site - Dallas
- NEO-811 Houston Site - Houston
Michigan
- NEO-811 Grand Rapids Site - Grand Rapids
South Carolina
- NEO-811 South Carolina Site - Myrtle Beach
Virginia
- NEO-811 Virginia Site - Fairfax
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 30 participants |
| Start Date | 2025-12-19 |
| Est. Completion | 2027-09 |
| Phase | Phase 1 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07300241
The ClinicalTrials.gov registry entry for NCT07300241 describes a study currently listed as recruiting, categorized as Phase 1. The registered enrollment target is 30 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 243-participant average among 121 other Renal Cell Carcinoma trials with a reported enrollment target (88% lower). The listed sponsor is Neomorph, which has 1 total studies on file at ClinicalTrials.gov.
The record links to 9 conditions, with Renal Cell Carcinoma appearing as the primary indexed condition, and to 1 intervention - of which NEO-811 is the first listed.
NCT07300241 reports 7 study locations spanning 5 distinct geographic areas - top geographies include New York, Texas, Michigan.
Frequently Asked Questions
What is clinical trial NCT07300241 about?
NCT07300241 is a clinical study titled "Open-Label Phase 1/2 Study of NEO-811 in Subjects With Locally Advanced or Metastatic Non-Resectable Clear Cell Renal Cell Carcinoma". The NEO-811-101 study is an open-label, first-in-human, Phase 1/2 dose escalation and expansion study of NEO-811 for subjects with locally advanced or metastatic non-resectable clear cell renal cell carcinoma. The study will test NEO-811 initially as a monotherapy.
What is the current status of trial NCT07300241?
This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 30 participants. The study started on 2025-12-19. Estimated completion is 2027-09.
What conditions does trial NCT07300241 study?
This clinical trial studies the following conditions: Renal Cell Carcinoma, Clear Cell Renal Cell Carcinoma, RCC, Kidney Cancers, Kidney Cancer Metastatic.
What interventions are being tested in trial NCT07300241?
The interventions under investigation include: NEO-811 (DRUG).
Who is sponsoring clinical trial NCT07300241?
This trial is sponsored by Neomorph, which has 1 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07300241 being conducted?
This trial has 7 study locations across Michigan, New York, South Carolina, Texas, Virginia. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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