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NCT07285668 · ClinicalTrials.gov registry record · NA

Prophylactic TCRaB+ and CD19+ Depleted Donor Lymphocyte Infusion After Allogeneic Stem Cell Transplant in High-Risk Patients With Hematologic Malignancies

A NA study of Hematologic Malignancies, sponsored by University of Wisconsin, Madison.

Recruiting
Registry status
NA
Development phase
38
Enrollment target
1
Study location

NCT07285668 is a NA study of Hematologic Malignancies that is actively recruiting participants, run by University of Wisconsin, Madison. The registered enrollment target is 38 participants, below the 2,711-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (99% lower). The trial reports 1 study location across 1 state.

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The verdict

NCT07285668, a NA study of Hematologic Malignancies, is actively recruiting participants, sponsored by University of Wisconsin, Madison.

RECRUITING
Registry status
NA
Development phase
38 participants
Enrollment target
1
Study location

Study Summary

This study is being done to assess the safety and determine the maximum tolerable dose (MTD) of TCRαβ+/CD19+-depleted Donor Lymphocyte Infusion (αβT/B dep-DLI) after allogeneic stem cell transplant (allo-SCT) in highrisk patients with hematologic malignancies.

Conditions Studied

Interventions

  • DEVICE Allogeneic donor TCRαβ+/CD19+ cell-depleted peripheral blood mononuclear cells

Study Locations (1)

Wisconsin

  • UW Carbone Cancer Center - Madison

Trial Details

FieldValue
Enrollment Target 38 participants
Start Date 2026-02-26
Est. Completion 2031-02
Phase NA

Sponsor

University of Wisconsin, Madison

1,039 total trials

What the Registry Record Tells You About NCT07285668

The ClinicalTrials.gov registry entry for NCT07285668 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 38 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 2,711-participant average among 45 other Hematologic Malignancies trials with a reported enrollment target (99% lower). The listed sponsor is University of Wisconsin, Madison, which has 1,039 total studies on file at ClinicalTrials.gov.

The record links to 1 condition, with Hematologic Malignancies appearing as the primary indexed condition, and to 1 intervention - of which Allogeneic donor TCRαβ+/CD19+ cell-depleted peripheral blood mononuclear cells is the first listed.

NCT07285668 reports 1 study location spanning 1 distinct geographic area - top geographies include Wisconsin.

Frequently Asked Questions

What is clinical trial NCT07285668 about?

NCT07285668 is a clinical study titled "Prophylactic TCRaB+ and CD19+ Depleted Donor Lymphocyte Infusion After Allogeneic Stem Cell Transplant in High-Risk Patients With Hematologic Malignancies". This study is being done to assess the safety and determine the maximum tolerable dose (MTD) of TCRαβ+/CD19+-depleted Donor Lymphocyte Infusion (αβT/B dep-DLI) after allogeneic stem cell transplant (allo-SCT) in highrisk patients with hematologic malignancies.

What is the current status of trial NCT07285668?

This trial is currently recruiting. It is a NA study. The enrollment target is 38 participants. The study started on 2026-02-26. Estimated completion is 2031-02.

What conditions does trial NCT07285668 study?

This clinical trial studies the following conditions: Hematologic Malignancies.

What interventions are being tested in trial NCT07285668?

The interventions under investigation include: Allogeneic donor TCRαβ+/CD19+ cell-depleted peripheral blood mononuclear cells (DEVICE).

Who is sponsoring clinical trial NCT07285668?

This trial is sponsored by University of Wisconsin, Madison, which has 1,039 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07285668 being conducted?

This trial has 1 study location across Wisconsin. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

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Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

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