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NCT07282834 · ClinicalTrials.gov registry record · Phase 2
Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)
A Phase 2 study of Peritoneal Carcinomatosis and Abdominal Cancer, sponsored by Patrick Wagner, MD, FACS.
- Recruiting
- Registry status
- Phase 2
- Development phase
- 200
- Enrollment target
- 1
- Study location
NCT07282834: Recruiting Phase 2 study of Peritoneal Carcinomatosis and Abdominal Cancer, sponsored by Patrick Wagner, MD, FACS.
NCT07282834 is a Phase 2 study of Peritoneal Carcinomatosis and Abdominal Cancer that is actively recruiting participants, run by Patrick Wagner, MD, FACS. The registered enrollment target is 200 participants, above the 45-participant average among 14 other Peritoneal Carcinomatosis trials with a reported enrollment target (344% higher). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07282834, a Phase 2 study of Peritoneal Carcinomatosis and Abdominal Cancer, is actively recruiting participants, sponsored by Patrick Wagner, MD, FACS.
- RECRUITING
- Registry status
- Phase 2
- Development phase
- 200 participants
- Enrollment target
- 1
- Study location
Study Summary
This research study aims to improve the treatment of Peritoneal Carcinomatosis (PC), a condition where cancer spreads within the abdomen. Patients with PC often experience significant pain and nutritional problems. Currently, there isn't a standard treatment approach, and doctors use different combinations of chemotherapy, surgery, and methods to deliver chemotherapy directly into the abdomen (intra-peritoneal or "IP" chemotherapy). The study will compare two IP chemotherapy methods: HIPEC and PIPAC. HIPEC involves circulating heated chemotherapy through the abdomen during surgery, while PIPAC delivers chemotherapy as a pressurized aerosol during a laparoscopic procedure. Both methods aim to achieve the same goal, but they haven't been directly compared to see which is safer, more tolerable, more effective, and provides better value.
Primary Outcome
Frequency of drug-related adverse events following HIPEC as assessed by CTCAE v5
Conditions Studied
Interventions
- PROCEDURE Heated intra-peritoneal chemotherapy
- PROCEDURE Aerosolized intra-peritoneal chemotherapy
Study Locations (1)
Pennsylvania
- Allegheny Health Network West Penn Hospital - Pittsburgh
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 200 participants |
| Start Date | 2026-01-05 |
| Est. Completion | 2040-11 |
| Phase | Phase 2 |
What NCT07282834 shows while recruiting
NCT07282834 is an interventional study that assigns participants to a tested intervention. The registered 200 participants enrollment target is mid-sized for trials with a published cap, above the 45-participant average among 14 other Peritoneal Carcinomatosis trials with a reported enrollment target (344% higher).
The record links to 4 conditions, with Peritoneal Carcinomatosis appearing as the primary indexed condition, and to 2 interventions - of which Heated intra-peritoneal chemotherapy is the first listed.
NCT07282834 reports a single indexed study location in Pennsylvania.
Frequently Asked Questions
What is clinical trial NCT07282834 about?
NCT07282834 is a clinical study titled "Heated Versus Aerosol-based Laparoscopic Chemotherapy for Cancer That Has Spread to the Peritoneum (Abdominal Lining)". This research study aims to improve the treatment of Peritoneal Carcinomatosis (PC), a condition where cancer spreads within the abdomen. Patients with PC often experience significant pain and nutritional problems. Currently, there isn't a standard treatment approach, and doctors use different combi...
What is the current status of trial NCT07282834?
This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 200 participants. The study started on 2026-01-05. Estimated completion is 2040-11.
What conditions does trial NCT07282834 study?
This clinical trial studies the following conditions: Peritoneal Carcinomatosis, Abdominal Cancer, Peritoneal (Metastatic) Cancer, Abdominal Cancer Patients.
What interventions are being tested in trial NCT07282834?
The interventions under investigation include: Heated intra-peritoneal chemotherapy (PROCEDURE), Aerosolized intra-peritoneal chemotherapy (PROCEDURE).
Who is sponsoring clinical trial NCT07282834?
This trial is sponsored by Patrick Wagner, MD, FACS, which has 2 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07282834 being conducted?
This trial has 1 study location across Pennsylvania. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Peritoneal Carcinomatosis
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07282834's enrollment target sits among peer trials
200 1st of 14 higher than 14 of 14 other Peritoneal Carcinomatosis trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Peritoneal Carcinomatosis trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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