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NCT07281547 · ClinicalTrials.gov registry record · Phase 4

Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain

A Phase 4 study, sponsored by Mayo Clinic.

Not yet
Registry status
Phase 4
Development phase
25
Enrollment target

NCT07281547: Clinical Trial Phase 4 study, sponsored by Mayo Clinic.

NCT07281547 is a Phase 4 study that has not yet begun recruiting, run by Mayo Clinic. The registered enrollment target is 25 participants. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07281547, a Phase 4 study, has not yet begun recruiting, sponsored by Mayo Clinic.

NOT YET RECRUITING
Registry status
Phase 4
Development phase
25 participants
Enrollment target

Study Summary

This phase IV trial studies whether low dose aspirin can be used to lower inflammation and prevent endometrial cancer in postmenopausal women with changes in the endometrial tissue that are not related to thinning (non-atrophic endometrial changes) and pain. As people age, there is an accumulation of fats, cell death, and inflammation, which causes a surge of pro-cancer-causing events. It is thought that there are several factors involved in the development of endometrial cancer, but that managing the inflammation may address the root cause. Low dose aspirin is aspirin that contains a lower dose than a standard adult tablet. Aspirin is a drug that reduces pain, fever, inflammation, and blood clotting. Aspirin belongs to the family of drugs called nonsteroidal anti-inflammatory agents. It is also being studied in cancer prevention. Giving low dose aspirin may be an effective way to lower inflammation and prevent endometrial cancer in postmenopausal women with non-atrophic endometrial changes and pain.

Interventions

  • PROCEDURE Biospecimen Collection
  • OTHER Questionnaire Administration
  • PROCEDURE Ultrasound Imaging
  • DRUG Low-Dose Aspirin
  • OTHER Patient Observation

Trial Details

FieldValue
Enrollment Target 25 participants
Start Date 2026-08-12
Est. Completion 2027-06-11
Phase Phase 4

Sponsor

Mayo Clinic

2,844 total trials

What the Registry Record Tells You About NCT07281547

The ClinicalTrials.gov registry entry for NCT07281547 describes a study currently listed as not yet recruiting, categorized as Phase 4. The registered enrollment target is 25 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Mayo Clinic, which has 2,844 total studies on file at ClinicalTrials.gov.

The record links to 0 conditions, and to 5 interventions - of which Biospecimen Collection is the first listed.

NCT07281547 reports 0 study locations.

Frequently Asked Questions

What is clinical trial NCT07281547 about?

NCT07281547 is a clinical study titled "Low Dose Aspirin to Lower Inflammation and Prevent Endometrial Cancer in Postmenopausal Women With Non-atrophic Endometrial Changes and Pain". This phase IV trial studies whether low dose aspirin can be used to lower inflammation and prevent endometrial cancer in postmenopausal women with changes in the endometrial tissue that are not related to thinning (non-atrophic endometrial changes) and pain. As people age, there is an accumulation o...

What is the current status of trial NCT07281547?

This trial is currently not yet recruiting. It is a Phase 4 study. The enrollment target is 25 participants. The study started on 2026-08-12. Estimated completion is 2027-06-11.

What interventions are being tested in trial NCT07281547?

The interventions under investigation include: Biospecimen Collection (PROCEDURE), Questionnaire Administration (OTHER), Ultrasound Imaging (PROCEDURE), Low-Dose Aspirin (DRUG), Patient Observation (OTHER).

Who is sponsoring clinical trial NCT07281547?

This trial is sponsored by Mayo Clinic, which has 2,844 total clinical trials registered on ClinicalTrials.gov.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, the data changelog, or report a data error.