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NCT07265557 · ClinicalTrials.gov registry record · NA

Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients

A NA study of Pain and Opioid, sponsored by Massachusetts General Hospital.

Recruiting
Registry status
NA
Development phase
100
Enrollment target
1
Study location

NCT07265557: Recruiting NA study of Pain and Opioid, sponsored by Massachusetts General Hospital.

NCT07265557 is a NA study of Pain and Opioid that is actively recruiting participants, run by Massachusetts General Hospital. The registered enrollment target is 100 participants, below the 304-participant average among 374 other Pain trials with a reported enrollment target (67% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07265557, a NA study of Pain and Opioid, is actively recruiting participants, sponsored by Massachusetts General Hospital.

RECRUITING
Registry status
NA
Development phase
100 participants
Enrollment target
1
Study location

Study Summary

This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioids) in patients undergoing major orthopaedic surgery. The main objective is to inform the design and feasibility of the definitive RCT.

Primary Outcome

Participant enrollment will be assessed by monitoring screening and enrollment metrics, including: * Participant enrollment * Feasibility of treatment allocation * Data collection methods (Proportion of participants with missing data) * Compliance with the protocol (Proportion of randomization errors, proportion of patients who complete each questionnaire at each of the follow-up, proportion of patients who withdraw from the trial, proportion of participants who are lost to follow-up)

Interventions

  • OTHER Discharge pain medication prescription

Study Locations (1)

Massachusetts

  • Mass - Boston

Trial Details

FieldValue
Enrollment Target 100 participants
Start Date 2025-10-06
Est. Completion 2026-05-31
Phase NA
Massachusetts General Hospital

2,032 total trials

What NCT07265557 shows while recruiting

NCT07265557 is an interventional study that assigns participants to a tested intervention. The registered 100 participants enrollment target is mid-sized for trials with a published cap, below the 304-participant average among 374 other Pain trials with a reported enrollment target (67% lower).

The record links to 4 conditions, with Pain appearing as the primary indexed condition, and to 1 intervention - of which Discharge pain medication prescription is the first listed.

NCT07265557 reports a single indexed study location in Massachusetts.

Frequently Asked Questions

What is clinical trial NCT07265557 about?

NCT07265557 is a clinical study titled "Two Post-Operative Pain Protocols at Discharge for Orthopaedic Patients". This is a single-center, pilot randomized controlled trial designed to evaluate the feasibility of a definitive trial comparing opioid-free discharge prescriptions to usual care (which includes opioids) in patients undergoing major orthopaedic surgery. The main objective is to inform the design and ...

What is the current status of trial NCT07265557?

This trial is currently recruiting. It is a NA study. The enrollment target is 100 participants. The study started on 2025-10-06. Estimated completion is 2026-05-31.

What conditions does trial NCT07265557 study?

This clinical trial studies the following conditions: Pain, Opioid, Pilot Study, Orthopaedic Related Pain (Musculoskeletal Pain).

What interventions are being tested in trial NCT07265557?

The interventions under investigation include: Discharge pain medication prescription (OTHER).

Who is sponsoring clinical trial NCT07265557?

This trial is sponsored by Massachusetts General Hospital, which has 2,032 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07265557 being conducted?

This trial has 1 study location across Massachusetts. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Pain

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07265557's enrollment target sits among peer trials

100 164th of 374 higher than 201 of 374 other Pain trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Pain trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07265557, the US trial registry maintained by the National Library of Medicine. NCT07265557 (mid enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.