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NCT07247058 · ClinicalTrials.gov registry record · Phase 4
Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)
A Phase 4 study of Mild Autonomous Cortisol Secretion (MACS), sponsored by Johns Hopkins University.
- Recruiting
- Registry status
- Phase 4
- Development phase
- 10
- Enrollment target
- 1
- Study location
NCT07247058 is a Phase 4 study of Mild Autonomous Cortisol Secretion (MACS) that is actively recruiting participants, run by Johns Hopkins University. The registered enrollment target is 10 participants. The trial reports 1 study location across 1 state.
The verdict
NCT07247058, a Phase 4 study of Mild Autonomous Cortisol Secretion (MACS), is actively recruiting participants, sponsored by Johns Hopkins University.
- RECRUITING
- Registry status
- Phase 4
- Development phase
- 10 participants
- Enrollment target
- 1
- Study location
Study Summary
To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Isturisa will exhibit significantly better metabolic indicators (such as fasting glucose, HbA1c, and lipid profile), blood pressure, weight, body composition and bone mineral density than at Baseline. The investigators also assess the effect of Isturisa on quality of life and psychological symptoms in patients with MACS. The investigators hypothesize that treatment with Isturisa will lead to significant improvements in quality-of-life scores and reductions in depression scores compared to Baseline.
Conditions Studied
Interventions
- DRUG Osilodrostat (Isturisa)
Study Locations (1)
Maryland
- Johns Hopkins University School of Medicine - Baltimore
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 10 participants |
| Start Date | 2026-02-02 |
| Est. Completion | 2029-03 |
| Phase | Phase 4 |
Interested in This Trial?
Full Details on ClinicalTrials.gov ↗What the Registry Record Tells You About NCT07247058
The ClinicalTrials.gov registry entry for NCT07247058 describes a study currently listed as recruiting, categorized as Phase 4. The registered enrollment target is 10 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is Johns Hopkins University, which has 1,448 total studies on file at ClinicalTrials.gov.
The record links to 1 condition, with Mild Autonomous Cortisol Secretion (MACS) appearing as the primary indexed condition, and to 1 intervention - of which Osilodrostat (Isturisa) is the first listed.
NCT07247058 reports 1 study location spanning 1 distinct geographic area - top geographies include Maryland.
Frequently Asked Questions
What is clinical trial NCT07247058 about?
NCT07247058 is a clinical study titled "Isturisa Treatment in Mild Autonomous Cortisol Secretion( MACS)". To characterize the impact of Isturisa on clinical features and comorbidities associated with MACS. The investigators hypothesize that patients treated with Isturisa will exhibit significantly better metabolic indicators (such as fasting glucose, HbA1c, and lipid profile), blood pressure, weight, bo...
What is the current status of trial NCT07247058?
This trial is currently recruiting. It is a Phase 4 study. The enrollment target is 10 participants. The study started on 2026-02-02. Estimated completion is 2029-03.
What conditions does trial NCT07247058 study?
This clinical trial studies the following conditions: Mild Autonomous Cortisol Secretion (MACS).
What interventions are being tested in trial NCT07247058?
The interventions under investigation include: Osilodrostat (Isturisa) (DRUG).
Who is sponsoring clinical trial NCT07247058?
This trial is sponsored by Johns Hopkins University, which has 1,448 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07247058 being conducted?
This trial has 1 study location across Maryland. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
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