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NCT07229417 · ClinicalTrials.gov registry record · Phase 2

IvoLoC Trial: A Phase II Trial Evaluating the Efficacy of Ivonescimab in Metastatic Endocrine Refractory HR-positive HER2-negative or Triple Negative Invasive Lobular Carcinoma

A Phase 2 study of Metastatic Endocrine Refractory and Triple Negative Invasive Lobular Carcinoma, sponsored by M.D. Anderson Cancer Center.

Recruiting
Registry status
Phase 2
Development phase
29
Enrollment target
1
Study location

NCT07229417 is a Phase 2 study of Metastatic Endocrine Refractory and Triple Negative Invasive Lobular Carcinoma that is actively recruiting participants, run by M.D. Anderson Cancer Center. The registered enrollment target is 29 participants. The trial reports 1 study location across 1 state.

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The verdict

NCT07229417, a Phase 2 study of Metastatic Endocrine Refractory and Triple Negative Invasive Lobular Carcinoma, is actively recruiting participants, sponsored by M.D. Anderson Cancer Center.

RECRUITING
Registry status
Phase 2
Development phase
29 participants
Enrollment target
1
Study location

Study Summary

To learn if ivonescimab can help to control endocrine-refractory HR+ HER2- and/or TN mILC.

Interventions

  • DRUG Ivonescimab

Study Locations (1)

Texas

  • MD Anderson Cancer Center - Houston

Trial Details

FieldValue
Enrollment Target 29 participants
Start Date 2025-10-22
Est. Completion 2029-09-30
Phase Phase 2

Sponsor

M.D. Anderson Cancer Center

2,692 total trials

What the Registry Record Tells You About NCT07229417

The ClinicalTrials.gov registry entry for NCT07229417 describes a study currently listed as recruiting, categorized as Phase 2. The registered enrollment target is 29 participants, a figure that helps gauge the scale of data the investigators plan to collect. The listed sponsor is M.D. Anderson Cancer Center, which has 2,692 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Metastatic Endocrine Refractory appearing as the primary indexed condition, and to 1 intervention - of which Ivonescimab is the first listed.

NCT07229417 reports 1 study location spanning 1 distinct geographic area - top geographies include Texas.

Frequently Asked Questions

What is clinical trial NCT07229417 about?

NCT07229417 is a clinical study titled "IvoLoC Trial: A Phase II Trial Evaluating the Efficacy of Ivonescimab in Metastatic Endocrine Refractory HR-positive HER2-negative or Triple Negative Invasive Lobular Carcinoma". To learn if ivonescimab can help to control endocrine-refractory HR+ HER2- and/or TN mILC.

What is the current status of trial NCT07229417?

This trial is currently recruiting. It is a Phase 2 study. The enrollment target is 29 participants. The study started on 2025-10-22. Estimated completion is 2029-09-30.

What conditions does trial NCT07229417 study?

This clinical trial studies the following conditions: Metastatic Endocrine Refractory, Triple Negative Invasive Lobular Carcinoma.

What interventions are being tested in trial NCT07229417?

The interventions under investigation include: Ivonescimab (DRUG).

Who is sponsoring clinical trial NCT07229417?

This trial is sponsored by M.D. Anderson Cancer Center, which has 2,692 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07229417 being conducted?

This trial has 1 study location across Texas. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.