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NCT07226011 · ClinicalTrials.gov registry record · NA
Accelerated High-Dose tDCS for Depression
A NA study of Major Depression and Major Depression Disorders, sponsored by Medical University of South Carolina.
- Recruiting
- Registry status
- NA
- Development phase
- 20
- Enrollment target
- 1
- Study location
NCT07226011: Recruiting NA study of Major Depression and Major Depression Disorders, sponsored by Medical University of South Carolina.
NCT07226011 is a NA study of Major Depression and Major Depression Disorders that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 20 participants, below the 327-participant average among 28 other Major Depression trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07226011, a NA study of Major Depression and Major Depression Disorders, is actively recruiting participants, sponsored by Medical University of South Carolina.
- RECRUITING
- Registry status
- NA
- Development phase
- 20 participants
- Enrollment target
- 1
- Study location
Study Summary
In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain Stimulation Lab and receive mild electrical stimulation through electrodes placed on their scalp. The study begins with a safety run-in, where the first few participants will receive stimulation at gradually increasing levels (2, 4, and 6 milliamps) while being closely monitored. If no serious side effects are found, later participants will receive repeated 6 milliamp sessions for 5 days total. Investigators will check skin comfort, mood, and overall tolerability after each session.
Primary Outcome
Defined as events requiring hospitalization or emergency care during the stimulation period.
Conditions Studied
Interventions
- DEVICE Transcranial Direct Current Stimulation (tDCS)
Study Locations (1)
South Carolina
- MUSC Brain Stimulation Lab - Charleston
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 20 participants |
| Start Date | 2025-12-15 |
| Est. Completion | 2026-06-01 |
| Phase | NA |
What NCT07226011 shows while recruiting
NCT07226011 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 20 participants, a relatively small participant target, below the 327-participant average among 28 other Major Depression trials with a reported enrollment target (94% lower).
The record links to 2 conditions, with Major Depression appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Direct Current Stimulation (tDCS) is the first listed.
NCT07226011 reports a single indexed study location in South Carolina.
Frequently Asked Questions
What is clinical trial NCT07226011 about?
NCT07226011 is a clinical study titled "Accelerated High-Dose tDCS for Depression". In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain Stimulation Lab and receive mild electrical stimulati...
What is the current status of trial NCT07226011?
This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-12-15. Estimated completion is 2026-06-01.
What conditions does trial NCT07226011 study?
This clinical trial studies the following conditions: Major Depression, Major Depression Disorders.
What interventions are being tested in trial NCT07226011?
The interventions under investigation include: Transcranial Direct Current Stimulation (tDCS) (DEVICE).
Who is sponsoring clinical trial NCT07226011?
This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07226011 being conducted?
This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Major Depression
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07226011's enrollment target sits among peer trials
20 26th of 28 higher than 3 of 28 other Major Depression trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Major Depression trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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