Medical Information Only. Always consult your healthcare provider before enrolling in any clinical trial.

NCT07226011 · ClinicalTrials.gov registry record · NA

Accelerated High-Dose tDCS for Depression

A NA study of Major Depression and Major Depression Disorders, sponsored by Medical University of South Carolina.

Recruiting
Registry status
NA
Development phase
20
Enrollment target
1
Study location

NCT07226011 is a NA study of Major Depression and Major Depression Disorders that is actively recruiting participants, run by Medical University of South Carolina. The registered enrollment target is 20 participants, below the 327-participant average among 28 other Major Depression trials with a reported enrollment target (94% lower). The trial reports 1 study location across 1 state.

View on ClinicalTrials.gov ↗

View your shortlist →

The verdict

NCT07226011, a NA study of Major Depression and Major Depression Disorders, is actively recruiting participants, sponsored by Medical University of South Carolina.

RECRUITING
Registry status
NA
Development phase
20 participants
Enrollment target
1
Study location

Study Summary

In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain Stimulation Lab and receive mild electrical stimulation through electrodes placed on their scalp. The study begins with a safety run-in, where the first few participants will receive stimulation at gradually increasing levels (2, 4, and 6 milliamps) while being closely monitored. If no serious side effects are found, later participants will receive repeated 6 milliamp sessions for 5 days total. Investigators will check skin comfort, mood, and overall tolerability after each session.

Interventions

  • DEVICE Transcranial Direct Current Stimulation (tDCS)

Study Locations (1)

South Carolina

  • MUSC Brain Stimulation Lab - Charleston

Trial Details

FieldValue
Enrollment Target 20 participants
Start Date 2025-12-15
Est. Completion 2026-06-01
Phase NA

What the Registry Record Tells You About NCT07226011

The ClinicalTrials.gov registry entry for NCT07226011 describes a study currently listed as recruiting, categorized as NA. The registered enrollment target is 20 participants, a figure that helps gauge the scale of data the investigators plan to collect, below the 327-participant average among 28 other Major Depression trials with a reported enrollment target (94% lower). The listed sponsor is Medical University of South Carolina, which has 755 total studies on file at ClinicalTrials.gov.

The record links to 2 conditions, with Major Depression appearing as the primary indexed condition, and to 1 intervention - of which Transcranial Direct Current Stimulation (tDCS) is the first listed.

NCT07226011 reports 1 study location spanning 1 distinct geographic area - top geographies include South Carolina.

Frequently Asked Questions

What is clinical trial NCT07226011 about?

NCT07226011 is a clinical study titled "Accelerated High-Dose tDCS for Depression". In this study, investigators are testing whether a higher dose of a non-invasive brain stimulation technique, called transcranial direct current stimulation (tDCS), can be safely used in people with depression. Participants will come to the Brain Stimulation Lab and receive mild electrical stimulati...

What is the current status of trial NCT07226011?

This trial is currently recruiting. It is a NA study. The enrollment target is 20 participants. The study started on 2025-12-15. Estimated completion is 2026-06-01.

What conditions does trial NCT07226011 study?

This clinical trial studies the following conditions: Major Depression, Major Depression Disorders.

What interventions are being tested in trial NCT07226011?

The interventions under investigation include: Transcranial Direct Current Stimulation (tDCS) (DEVICE).

Who is sponsoring clinical trial NCT07226011?

This trial is sponsored by Medical University of South Carolina, which has 755 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07226011 being conducted?

This trial has 1 study location across South Carolina. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Major Depression

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Data sourced from official public datasets. See our methodology for details. Retrieved and formatted by PlainTrial Editorial

Every figure on PlainTrial is rendered directly from the ClinicalTrials.gov registry, no number is typed in by an editor. This page mirrors this trial's own ClinicalTrials.gov registry record, live from the dataset. See our editorial standards & corrections policy, the methodology behind these numbers, or report a data error.