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NCT07225816 · ClinicalTrials.gov registry record · Phase 1

Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)

A Phase 1 study of Obesity, sponsored by Novo Nordisk A/S.

Recruiting
Registry status
Phase 1
Development phase
75
Enrollment target
1
Study location

NCT07225816: Recruiting Phase 1 study of Obesity, sponsored by Novo Nordisk A/S.

NCT07225816 is a Phase 1 study of Obesity that is actively recruiting participants, run by Novo Nordisk A/S. The registered enrollment target is 75 participants, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.

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The verdict

NCT07225816, a Phase 1 study of Obesity, is actively recruiting participants, sponsored by Novo Nordisk A/S.

RECRUITING
Registry status
Phase 1
Development phase
75 participants
Enrollment target
1
Study location

Study Summary

The purpose of this study is to investigate how the duration of fasting and temporary stopping of Glucagon-Like-Peptide 1 (GLP-1) medications affect the amount of food left in the stomach in people using liraglutide (injected), semaglutide (taken by mouth) or semaglutide (injected). The length of participants participation in the study will depend on the type of GLP-1 RA treatment participants are already using.

Primary Outcome

Measured as count of participants.

Conditions Studied

Interventions

  • DRUG Semaglutide
  • DRUG Liraglutide
  • DRUG Oral Semaglutide

Study Locations (1)

California

  • Altasciences Clinical LA, Inc. - Cypress

Trial Details

FieldValue
Enrollment Target 75 participants
Start Date 2025-11-07
Est. Completion 2026-07-17
Phase Phase 1
Novo Nordisk A/S

431 total trials

What NCT07225816 shows while recruiting

NCT07225816 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 75 participants, a relatively small participant target, below the 819-participant average among 1,053 other Obesity trials with a reported enrollment target (91% lower).

The record links to 1 condition, with Obesity appearing as the primary indexed condition, and to 3 interventions - of which Semaglutide is the first listed.

NCT07225816 reports a single indexed study location in California.

Frequently Asked Questions

What is clinical trial NCT07225816 about?

NCT07225816 is a clinical study titled "Examination of How the Duration of Fasting and Temporary Stopping of GLP-1 Medications Affect the Amount of Food Left in the Stomach in People Using Liraglutide (Injected), Semaglutide (Taken by Mouth) or Semaglutide (Injected)". The purpose of this study is to investigate how the duration of fasting and temporary stopping of Glucagon-Like-Peptide 1 (GLP-1) medications affect the amount of food left in the stomach in people using liraglutide (injected), semaglutide (taken by mouth) or semaglutide (injected). The length of pa...

What is the current status of trial NCT07225816?

This trial is currently recruiting. It is a Phase 1 study. The enrollment target is 75 participants. The study started on 2025-11-07. Estimated completion is 2026-07-17.

What conditions does trial NCT07225816 study?

This clinical trial studies the following conditions: Obesity.

What interventions are being tested in trial NCT07225816?

The interventions under investigation include: Semaglutide (DRUG), Liraglutide (DRUG), Oral Semaglutide (DRUG).

Who is sponsoring clinical trial NCT07225816?

This trial is sponsored by Novo Nordisk A/S, which has 431 total clinical trials registered on ClinicalTrials.gov.

Where is trial NCT07225816 being conducted?

This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.

Similar trials for Obesity

Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.

Where NCT07225816's enrollment target sits among peer trials

75 570th of 1053 higher than 481 of 1,053 other Obesity trials

participants (enrollment target), bucketed by value

Each bar is a band; taller bars hold more other Obesity trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.

Source ClinicalTrials.gov registry export · 2026-08-08

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Source: ClinicalTrials.gov NCT07225816, the US trial registry maintained by the National Library of Medicine. NCT07225816 (small enrollment · single site footprint · recruiting) retrieved and formatted by PlainTrial, see methodology.