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NCT07224789 · ClinicalTrials.gov registry record
Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA
A clinical trial of Colorectal Cancer, sponsored by City of Hope Medical Center.
- Recruiting
- Registry status
- 600
- Enrollment target
- 1
- Study location
NCT07224789: Recruiting study of Colorectal Cancer, sponsored by City of Hope Medical Center.
NCT07224789 is a study of Colorectal Cancer that is actively recruiting participants, run by City of Hope Medical Center. The registered enrollment target is 600 participants, below the 1,543-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (61% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07224789, a study of Colorectal Cancer, is actively recruiting participants, sponsored by City of Hope Medical Center.
- RECRUITING
- Registry status
- 600 participants
- Enrollment target
- 1
- Study location
Study Summary
Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.
Primary Outcome
Proportion of early-stage (Stage I-II) colorectal cancer patients correctly identified as positive by the circRNA-based diagnostic model.
Conditions Studied
Interventions
- DIAGNOSTIC_TEST cf-circRNA assay
Study Locations (1)
California
- City of Hope Medical Center - Duarte
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 600 participants |
| Start Date | 2025-01-15 |
| Est. Completion | 2026-06-18 |
What NCT07224789 shows while recruiting
NCT07224789 is an observational study that tracks outcomes without assigning an intervention. The registered 600 participants enrollment target is mid-sized for trials with a published cap, below the 1,543-participant average among 381 other Colorectal Cancer trials with a reported enrollment target (61% lower).
The record links to 1 condition, with Colorectal Cancer appearing as the primary indexed condition, and to 1 intervention - of which cf-circRNA assay is the first listed.
NCT07224789 reports a single indexed study location in California.
Frequently Asked Questions
What is clinical trial NCT07224789 about?
NCT07224789 is a clinical study titled "Liquid Biopsy for Early Detection of Colorectal Cancer Using Circular RNA". Colorectal cancer (CRC) is a leading cause of cancer-related deaths worldwide. This study aims to develop a non-invasive liquid biopsy assay using plasma-derived cell-free circular RNAs (cf-circRNAs) for early and accurate detection of colorectal cancer.
What is the current status of trial NCT07224789?
This trial is currently recruiting. The enrollment target is 600 participants. The study started on 2025-01-15. Estimated completion is 2026-06-18.
What conditions does trial NCT07224789 study?
This clinical trial studies the following conditions: Colorectal Cancer.
What interventions are being tested in trial NCT07224789?
The interventions under investigation include: cf-circRNA assay (DIAGNOSTIC_TEST).
Who is sponsoring clinical trial NCT07224789?
This trial is sponsored by City of Hope Medical Center, which has 582 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07224789 being conducted?
This trial has 1 study location across California. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Colorectal Cancer
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07224789's enrollment target sits among peer trials
600 73rd of 381 higher than 309 of 381 other Colorectal Cancer trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Colorectal Cancer trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
Source ClinicalTrials.gov registry export · 2026-08-08
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