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NCT07222098 · ClinicalTrials.gov registry record · Phase 1
A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)
A Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
- Completed
- Registry status
- Phase 1
- Development phase
- 16
- Enrollment target
- 1
- Study location
NCT07222098: Completed Phase 1 study of Healthy, sponsored by Merck Sharp & Dohme.
NCT07222098 is a Phase 1 study of Healthy that has completed, run by Merck Sharp & Dohme. The registered enrollment target is 16 participants, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower). The trial reports 1 study location across 1 state. According to ClinicalTrials.gov, the official US trial registry.
The verdict
NCT07222098, a Phase 1 study of Healthy, has completed, sponsored by Merck Sharp & Dohme.
- COMPLETED
- Registry status
- Phase 1
- Development phase
- 16 participants
- Enrollment target
- 1
- Study location
Study Summary
Researchers want to learn about calderasib when given with rosuvastatin and metformin in healthy people. The goal of this study is to compare the amount of rosuvastatin and metformin in a person's body over time when given with and without calderasib
Primary Outcome
Blood samples will be collected at multiple time points to determine the AUC0-inf of rosuvastatin
Conditions Studied
Interventions
- DRUG Metformin
- DRUG Calderasib
- DRUG Rosuvastatin
Study Locations (1)
Nebraska
- Celerion ( Site 0001) - Lincoln
Trial Details
| Field | Value |
|---|---|
| Enrollment Target | 16 participants |
| Start Date | 2025-11-19 |
| Est. Completion | 2025-12-23 |
| Phase | Phase 1 |
What the finished NCT07222098 record still lists
NCT07222098 is an interventional study that assigns participants to a tested intervention. The registry caps enrollment at 16 participants, a relatively small participant target, below the 647-participant average among 1,090 other Healthy trials with a reported enrollment target (98% lower).
The record links to 1 condition, with Healthy appearing as the primary indexed condition, and to 3 interventions - of which Metformin is the first listed.
NCT07222098 reports a single indexed study location in Nebraska.
Frequently Asked Questions
What is clinical trial NCT07222098 about?
NCT07222098 is a clinical study titled "A Clinical Study of Calderasib (MK-1084) With Rosuvastatin and Metformin in Healthy People (MK-1084-016)". Researchers want to learn about calderasib when given with rosuvastatin and metformin in healthy people. The goal of this study is to compare the amount of rosuvastatin and metformin in a person's body over time when given with and without calderasib
What is the current status of trial NCT07222098?
This trial is currently completed. It is a Phase 1 study. The enrollment target is 16 participants. The study started on 2025-11-19. Estimated completion is 2025-12-23.
What conditions does trial NCT07222098 study?
This clinical trial studies the following conditions: Healthy.
What interventions are being tested in trial NCT07222098?
The interventions under investigation include: Metformin (DRUG), Calderasib (DRUG), Rosuvastatin (DRUG).
Who is sponsoring clinical trial NCT07222098?
This trial is sponsored by Merck Sharp & Dohme, which has 558 total clinical trials registered on ClinicalTrials.gov.
Where is trial NCT07222098 being conducted?
This trial has 1 study location across Nebraska. Contact the study sites directly through ClinicalTrials.gov for enrollment availability.
Learn More About Clinical Trials
Similar trials for Healthy
Matched on the same primary condition, ranked to surface studies in the same phase first, then by recruiting status, no relevance scoring or editorial curation.
Where NCT07222098's enrollment target sits among peer trials
16 936th of 1090 higher than 137 of 1,090 other Healthy trials
participants (enrollment target), bucketed by value
Each bar is a band; taller bars hold more other Healthy trials. The dashed line + filled bar mark this entry. Hover or tap any bar for its full count and share, and where it sits relative to this entry.
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